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PAP12 purple acid phosphatase 12 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817261, updated on 18-Sep-2024

Summary

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Official Symbol
PAP12
Official Full Name
purple acid phosphatase 12
Primary source
TAIR:AT2G27190
Locus tag
AT2G27190
See related
Araport:AT2G27190
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ARABIDOPSIS THALIANA PURPLE ACID PHOSPHATASE 1; ATPAP1; ATPAP12; PAP1; PURPLE ACID PHOSPHATASE 1; purple acid phosphatase 12; PURPLE ACID PHOSPHATASE 12; SECRETED PURPLE ACID PHOSPHATASE PRECURSOR; T22O13.4; T22O13_4
Summary
Encodes a root-secreted purple acid phosphatase involved in extracellular phosphate-scavenging.
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Genomic context

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See PAP12 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
7
Sequence:
Chromosome: 2; NC_003071.7 (11621222..11623618, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Structural maintenance of chromosomes (SMC) family protein Neighboring gene uncharacterized protein Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene BRI1 suppressor 1 (BSU1)-like 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The secreted purple acid phosphatase isozymes AtPAP12 and AtPAP26 play a pivotal role in extracellular phosphate-scavenging by Arabidopsis thaliana. Robinson WD, et al. J Exp Bot, 2012 Nov. PMID 23125358, Free PMC Article
  2. Biochemical and molecular characterization of AtPAP12 and AtPAP26: the predominant purple acid phosphatase isozymes secreted by phosphate-starved Arabidopsis thaliana. Tran HT, et al. Plant Cell Environ, 2010 Nov. PMID 20545876
  3. A chloroplast phosphate transporter, PHT2;1, influences allocation of phosphate within the plant and phosphate-starvation responses. Versaw WK, et al. Plant Cell, 2002 Aug. PMID 12172020, Free PMC Article
  4. Comparative genetic analysis of Arabidopsis purple acid phosphatases AtPAP10, AtPAP12, and AtPAP26 provides new insights into their roles in plant adaptation to phosphate deprivation. Wang L, et al. J Integr Plant Biol, 2014 Mar. PMID 24528675
  5. Purple acid phosphatases of Arabidopsis thaliana. Comparative analysis and differential regulation by phosphate deprivation. Li D, et al. J Biol Chem, 2002 Aug 2. PMID 12021284

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. AtPAP12 and AtPAP26 are two major intracellular and secreted acid phosphatases (APases) in Arabidopsis while AtPAP10 is mainly a secreted APase.
    Title: Comparative genetic analysis of Arabidopsis purple acid phosphatases AtPAP10, AtPAP12, and AtPAP26 provides new insights into their roles in plant adaptation to phosphate deprivation.
  2. An Arabidopsis thaliana purple acid phosphatase atpap26/atpap12 T-DNA double insertion mutant impaired growth and produced >60 and >30% decreases in root secretory APase activity and rosette total inorganic phosphorus concentration, respectively.
    Title: The secreted purple acid phosphatase isozymes AtPAP12 and AtPAP26 play a pivotal role in extracellular phosphate-scavenging by Arabidopsis thaliana.
  3. AtPAP12 and AtPAP26 facilitate Pi scavenging from soil-localized organophosphates during nutritional Pi deprivation.
    Title: Biochemical and molecular characterization of AtPAP12 and AtPAP26: the predominant purple acid phosphatase isozymes secreted by phosphate-starved Arabidopsis thaliana.
Submit: New GeneRIF Correction

General gene information

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NM_128277.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables acid phosphatase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables acid phosphatase activity ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to phosphate starvation IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
purple acid phosphatase 12
NP_180287.2
  • purple acid phosphatase 12 (PAP12); FUNCTIONS IN: protein serine/threonine phosphatase activity, acid phosphatase activity; INVOLVED IN: cellular response to phosphate starvation; LOCATED IN: plant-type cell wall; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Purple acid phosphatase, N-terminal (InterPro:IPR015914), Metallophosphoesterase (InterPro:IPR004843), Purple acid phosphatase-like, N-terminal (InterPro:IPR008963); BEST Arabidopsis thaliana protein match is: purple acid phosphatase 10 (TAIR:AT2G16430.2); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    11621222..11623618 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128277.5 → NP_180287.2  purple acid phosphatase 12 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180287.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q38924, Q42349, Q540Q7, Q8VZC6, Q9SHS9
    UniProtKB/TrEMBL
    A0A654EWP1
    Conserved Domains (3) summary
    cd00839
    Location:157 → 455
    MPP_PAPs; purple acid phosphatases of the metallophosphatase superfamily, metallophosphatase domain
    pfam00149
    Location:161 → 360
    Metallophos; Calcineurin-like phosphoesterase
    pfam16656
    Location:60 → 149
    Pur_ac_phosph_N; Purple acid Phosphatase, N-terminal domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q38924.3

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