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ALPHA-VPE alpha-vacuolar processing enzyme [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817135, updated on 18-Sep-2024

Summary

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Official Symbol
ALPHA-VPE
Official Full Name
alpha-vacuolar processing enzyme
Primary source
TAIR:AT2G25940
Locus tag
AT2G25940
See related
Araport:AT2G25940
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
alpha-vacuolar processing enzyme; ALPHAVPE; F17H15.4
Summary
Encodes a vacuolar processing enzyme belonging to a novel group of cysteine proteinases that is expressed in vegetative organs and is upregulated in association with various types of cell death and under stressed conditions.
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Genomic context

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See ALPHA-VPE in Genome Data Viewer
Location:
chromosome: 2
Exon count:
8
Sequence:
Chromosome: 2; NC_003071.7 (11063301..11066184, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene pollen-specific LRR extensin-like protein Neighboring gene ncRNA Neighboring gene hydroxyproline-rich glycoprotein family protein Neighboring gene PITH domain protein (DUF1000) Neighboring gene uncharacterized protein Neighboring gene KH domain-containing protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Homologues of a vacuolar processing enzyme that are expressed in different organs in Arabidopsis thaliana. Kinoshita T, et al. Plant Mol Biol, 1995 Oct. PMID 7579169
  2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

General gene information

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NM_128154.5

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vacuolar protein processing ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  
located_in protein storage vacuole ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in vacuole ISS
Inferred from Sequence or Structural Similarity
more info
 PubMed 

General protein information

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Preferred Names
alpha-vacuolar processing enzyme
NP_180165.1
  • alpha-vacuolar processing enzyme (ALPHA-VPE); FUNCTIONS IN: cysteine-type endopeptidase activity; INVOLVED IN: proteolysis, vacuolar protein processing; LOCATED IN: endomembrane system; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Peptidase C13, legumain (InterPro:IPR001096); BEST Arabidopsis thaliana protein match is: gamma vacuolar processing enzyme (TAIR:AT4G32940.1); Has 793 Blast hits to 791 proteins in 239 species: Archae - 4; Bacteria - 12; Metazoa - 278; Fungi - 115; Plants - 259; Viruses - 0; Other Eukaryotes - 125 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    11063301..11066184 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_128154.5 → NP_180165.1  alpha-vacuolar processing enzyme [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_180165.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O82806, P49047, Q7GAI8
    UniProtKB/TrEMBL
    A0A178VQP4
    Conserved Domains (1) summary
    pfam01650
    Location:44 → 314
    Peptidase_C13; Peptidase C13 family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P49047.2

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