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ARF3 ADP-ribosylation factor 3 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 817014, updated on 18-Sep-2024

Summary

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Official Symbol
ARF3
Official Full Name
ADP-ribosylation factor 3
Primary source
TAIR:AT2G24765
Locus tag
AT2G24765
See related
Araport:AT2G24765
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ADP-ribosylation factor 3; ARF-LIKE 1; ARL1; ATARL1; F27A10.8
Summary
GTPase required for Golgi targeting of GRIP domain proteins. AtARL1 binds directly to the GRIP domain of AtGRIP in a GTP-dependent manner
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Genomic context

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See ARF3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
8
Sequence:
Chromosome: 2; NC_003071.7 (10562688..10565296)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene glutamine dumper 4 Neighboring gene uncharacterized protein Neighboring gene CONSTANS-like 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. AUXIN RESPONSE FACTOR3 Regulates Floral Meristem Determinacy by Repressing Cytokinin Biosynthesis and Signaling. Zhang K, et al. Plant Cell, 2018 Feb. PMID 29371438, Free PMC Article
  2. tasiRNA-ARF pathway moderates floral architecture in Arabidopsis plants subjected to drought stress. Matsui A, et al. Biomed Res Int, 2014. PMID 25243128, Free PMC Article
  3. Pattern of auxin and cytokinin responses for shoot meristem induction results from the regulation of cytokinin biosynthesis by AUXIN RESPONSE FACTOR3. Cheng ZJ, et al. Plant Physiol, 2013 Jan. PMID 23124326, Free PMC Article
  4. ARF3-Mediated Regulation of SPL in Early Anther Morphogenesis: Maintaining Precise Spatial Distribution and Expression Level. Yang Q, et al. Int J Mol Sci, 2023 Jul 21. PMID 37511499, Free PMC Article
  5. ARL1 plays a role in the binding of the GRIP domain of a peripheral matrix protein to the Golgi apparatus in plant cells. Stefano G, et al. Plant Mol Biol, 2006 Jun. PMID 16830178

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. ARF3-Mediated Regulation of SPL in Early Anther Morphogenesis: Maintaining Precise Spatial Distribution and Expression Level.
    Title: ARF3-Mediated Regulation of SPL in Early Anther Morphogenesis: Maintaining Precise Spatial Distribution and Expression Level.
  2. Regulation of Female Germline Specification via Small RNA Mobility in Arabidopsis.
    Title: Regulation of Female Germline Specification via Small RNA Mobility in Arabidopsis.
  3. ARF3 controls cell division by regulating cell cycle gene expression through cytokinin.
    Title: AUXIN RESPONSE FACTOR3 Regulates Floral Meristem Determinacy by Repressing Cytokinin Biosynthesis and Signaling.
  4. AS2, RH10 and NUC1 maintain cytosine methylations at specific sets of CpG sites in exon 6 of ARF3.
    Title: Arabidopsis Zinc-Finger-Like Protein ASYMMETRIC LEAVES2 (AS2) and Two Nucleolar Proteins Maintain Gene Body DNA Methylation in the Leaf Polarity Gene ETTIN (ARF3).
  5. Results indicate that auxin response factors AtARF2-AtARF4 and AtARF5 play significant roles in regulating both female and male gametophyte development.
    Title: ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.
  6. Analysis of ta-siRNA synthesis mutants and mutated ARF3-overexpressing plants that escape the tasiRNA-ARF target indicated that self-pollination was hampered by short stamens in plants under drought and high-salinity stress.
    Title: tasiRNA-ARF pathway moderates floral architecture in Arabidopsis plants subjected to drought stress.
  7. ARF3 is a direct target of AP2 and partially mediates AP2's function in floral meristem determinacy.ARF3 integrates the functions of AGAMOUS and APETALA2 in floral meristem determinacy.
    Title: AUXIN RESPONSE FACTOR 3 integrates the functions of AGAMOUS and APETALA2 in floral meristem determinacy.
  8. ARF3 mediates the auxin response during de novo shoot regeneration.
    Title: Pattern of auxin and cytokinin responses for shoot meristem induction results from the regulation of cytokinin biosynthesis by AUXIN RESPONSE FACTOR3.
  9. AS1 binds the ETT promoter. An upstream region of ETT directs transcriptional repression by AS1 and AS2. AS2 requires AS1 to regulate ETT expression directly.
    Title: Dual regulation of ETTIN (ARF3) gene expression by AS1-AS2, which maintains the DNA methylation level, is involved in stabilization of leaf adaxial-abaxial partitioning in Arabidopsis.
  10. ARL1(AT2G24765) is associated with the localization of peripheral golgins to the plant Golgi apparatus.
    Title: ARL1 plays a role in the binding of the GRIP domain of a peripheral matrix protein to the Golgi apparatus in plant cells.
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Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_001084486.1
NM_179726.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus ISM
Inferred from Sequence Model
more info
  
located_in Golgi stack IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane HDA PubMed 

General protein information

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Preferred Names
ADP-ribosylation factor 3
NP_001077955.1
  • ADP-ribosylation factor 3 (ARF3); FUNCTIONS IN: protein binding; INVOLVED IN: N-terminal protein myristoylation; LOCATED IN: Golgi stack, plasma membrane, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: ADP-ribosylation factor (InterPro:IPR006688), ARF/SAR superfamily (InterPro:IPR006689); BEST Arabidopsis thaliana protein match is: ADP-ribosylation factor A1B (TAIR:AT5G14670.1); Has 9110 Blast hits to 9109 proteins in 393 species: Archae - 2; Bacteria - 4; Metazoa - 4531; Fungi - 1457; Plants - 1456; Viruses - 3; Other Eukaryotes - 1657 (source: NCBI BLink).
NP_850057.1
  • ADP-ribosylation factor 3 (ARF3); FUNCTIONS IN: protein binding; INVOLVED IN: response to cadmium ion, N-terminal protein myristoylation; LOCATED IN: Golgi stack, plasma membrane, membrane; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: ADP-ribosylation factor (InterPro:IPR006688), Small GTP-binding protein (InterPro:IPR005225), Small GTPase SAR1-type (InterPro:IPR006687), ARF/SAR superfamily (InterPro:IPR006689); BEST Arabidopsis thaliana protein match is: ADP-ribosylation factor A1B (TAIR:AT5G14670.1); Has 11503 Blast hits to 11498 proteins in 430 species: Archae - 12; Bacteria - 8; Metazoa - 5738; Fungi - 1713; Plants - 1591; Viruses - 3; Other Eukaryotes - 2438 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    10562688..10565296
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_179726.3 → NP_850057.1  ADP-ribosylation factor 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_850057.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A8MRA0, P40940, Q541X9
    UniProtKB/TrEMBL
    A0A178VQT4, A0A5S9X179
    Conserved Domains (1) summary
    cd04151
    Location:19 → 176
    Arl1; ADP ribosylation factor 1 (Arf1)

  2. NM_001084486.1 → NP_001077955.1  ADP-ribosylation factor 3 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001077955.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    P40940
    Conserved Domains (1) summary
    cl21455
    Location:19 → 128
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P40940.2

Gene LinkOut

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