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LIP1 lipoic acid synthase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816619, updated on 18-Sep-2024

Summary

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Official Symbol
LIP1
Official Full Name
lipoic acid synthase 1
Primary source
TAIR:AT2G20860
Locus tag
AT2G20860
See related
Araport:AT2G20860
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F5H14.17; F5H14_17; lipoic acid synthase 1
Summary
LIP1,Lipoic acid synthase
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Genomic context

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See LIP1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
5
Sequence:
Chromosome: 2; NC_003071.7 (8979554..8981923)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Secretory carrier membrane protein (SCAMP) family protein Neighboring gene STRUBBELIG-receptor family 1 Neighboring gene cell wall protein precursor Neighboring gene uncharacterized protein Neighboring gene epidermal patterning factor 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Biosynthesis of lipoic acid in Arabidopsis: cloning and characterization of the cDNA for lipoic acid synthase. Yasuno R, et al. Plant Physiol, 1998 Nov. PMID 9808738, Free PMC Article
  2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

NM_001335714.1
NM_001335715.1

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables lipoate synthase activity IEA
Inferred from Electronic Annotation
more info
  
enables lipoate synthase activity IGI
Inferred from Genetic Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within glycine catabolic process TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within lipoate biosynthetic process IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within lipoate biosynthetic process TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in mitochondrial matrix IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
lipoic acid synthase 1
NP_001318257.1
  • LIPOIC ACID SYNTHASE 1 (LIP1); FUNCTIONS IN: lipoic acid synthase activity; INVOLVED IN: lipoic acid biosynthetic process, glycine catabolic process; LOCATED IN: mitochondrion, mitochondrial matrix; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Aldolase-type TIM barrel (InterPro:IPR013785), Lipoate synthase (InterPro:IPR003698), Elongator protein 3/MiaB/NifB (InterPro:IPR006638), Radical SAM (InterPro:IPR007197); BEST Arabidopsis thaliana protein match is: lipoic acid synthase family protein (TAIR:AT5G08415.1); Has 5683 Blast hits to 5683 proteins in 1186 species: Archae - 36; Bacteria - 2370; Metazoa - 113; Fungi - 91; Plants - 53; Viruses - 0; Other Eukaryotes - 3020 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    8979554..8981923
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127655.4 → NP_179682.1  lipoic acid synthase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179682.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9ZWT1
    UniProtKB/TrEMBL
    A0A178VME8, A0A5S9WZR5, A0A654EW98
    Conserved Domains (1) summary
    PLN02428
    Location:23 → 372
    PLN02428; lipoic acid synthase

  2. NM_001335714.1 → NP_001318257.1  lipoic acid synthase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9ZWT1
    UniProtKB/TrEMBL
    A0A178VME8, A0A5S9WZR5, A0A654EW98
    Conserved Domains (1) summary
    PLN02428
    Location:23 → 372
    PLN02428; lipoic acid synthase

  3. NM_001335715.1 → NP_001323612.1  lipoic acid synthase 1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9ZWT1
    UniProtKB/TrEMBL
    A0A178VME8, A0A5S9WZR5, A0A654EW98
    Conserved Domains (1) summary
    PLN02428
    Location:23 → 372
    PLN02428; lipoic acid synthase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZWT1.1

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