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NDB4 NAD(P)H dehydrogenase B4 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816609, updated on 18-Sep-2024

Summary

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Official Symbol
NDB4
Official Full Name
NAD(P)H dehydrogenase B4
Primary source
TAIR:AT2G20800
Locus tag
AT2G20800
See related
Araport:AT2G20800
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F5H14.23; F5H14_23; NAD(P)H dehydrogenase B4
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Genomic context

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See NDB4 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
6
Sequence:
Chromosome: 2; NC_003071.7 (8953057..8955831, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene GCR2-like 2 Neighboring gene Major facilitator superfamily protein Neighboring gene clathrin adaptor complexes medium subunit family protein Neighboring gene uncharacterized protein Neighboring gene DNA-binding storekeeper protein transcriptional regulator-like protein Neighboring gene galacturonosyltransferase 10 Neighboring gene QWRF motif protein (DUF566)

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alterations in the mitochondrial alternative NAD(P)H Dehydrogenase NDB4 lead to changes in mitochondrial electron transport chain composition, plant growth and response to oxidative stress. Smith C, et al. Plant Cell Physiol, 2011 Jul. PMID 21659327
  2. Arabidopsis genes encoding mitochondrial type II NAD(P)H dehydrogenases have different evolutionary origin and show distinct responses to light. Michalecka AM, et al. Plant Physiol, 2003 Oct. PMID 12972666, Free PMC Article
  3. Galacturonosyltransferase (GAUT)1 and GAUT7 are the core of a plant cell wall pectin biosynthetic homogalacturonan:galacturonosyltransferase complex. Atmodjo MA, et al. Proc Natl Acad Sci U S A, 2011 Dec 13. PMID 22135470, Free PMC Article
  4. The hydrophobic proteome of mitochondrial membranes from Arabidopsis cell suspensions. Brugière S, et al. Phytochemistry, 2004 Jun. PMID 15276431
  5. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Altered NDB4 expression affects expression of other genes involved in the alternative respiratory pathway, ROS levels and cellular NAD(P)H activity. nts with altered NDB4 expression show tolerance to salt stress.
    Title: Alterations in the mitochondrial alternative NAD(P)H Dehydrogenase NDB4 lead to changes in mitochondrial electron transport chain composition, plant growth and response to oxidative stress.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_127645.4

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables NADH dehydrogenase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
  
enables oxidoreductase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in NADH oxidation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chloroplast ISM
Inferred from Sequence Model
more info
  
located_in mitochondrial intermembrane space ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
NAD(P)H dehydrogenase B4
NP_179673.1
  • NAD(P)H dehydrogenase B4 (NDB4); FUNCTIONS IN: NADH dehydrogenase activity; INVOLVED IN: oxidation reduction; LOCATED IN: extrinsic to mitochondrial inner membrane, mitochondrion, plastid; EXPRESSED IN: 7 plant structures; CONTAINS InterPro DOMAIN/s: Pyridine nucleotide-disulphide oxidoreductase, class-II (InterPro:IPR000103), FAD-dependent pyridine nucleotide-disulphide oxidoreductase (InterPro:IPR013027), Pyridine nucleotide-disulphide oxidoreductase, NAD-binding region (InterPro:IPR001327), EF-HAND 2 (InterPro:IPR018249); BEST Arabidopsis thaliana protein match is: NAD(P)H dehydrogenase B3 (TAIR:AT4G21490.1); Has 11460 Blast hits to 10815 proteins in 2238 species: Archae - 334; Bacteria - 8988; Metazoa - 48; Fungi - 603; Plants - 426; Viruses - 0; Other Eukaryotes - 1061 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    8953057..8955831 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127645.4 → NP_179673.1  NAD(P)H dehydrogenase B4 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179673.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9SKT7
    UniProtKB/TrEMBL
    A0A5S9WZQ1, A0A654EW89
    Conserved Domains (2) summary
    PTZ00318
    Location:61 → 582
    PTZ00318; NADH dehydrogenase-like protein; Provisional
    cl21454
    Location:265 → 311
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SKT7.1

Gene LinkOut

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