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MUR3 Exostosin family protein [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816556, updated on 18-Sep-2024

Summary

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Official Symbol
MUR3
Official Full Name
Exostosin family protein
Primary source
TAIR:AT2G20370
Locus tag
AT2G20370
See related
Araport:AT2G20370
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
AtMUR3; F11A3.8; F11A3_8; KAM1; KATAMARI 1; MURUS 3; RSA3; SHORT ROOT IN SALT MEDIUM 3
Summary
Encodes a xyloglucan galactosyltransferase located in the membrane of Golgi stacks that is involved in the biosynthesis of fucose. It is also involved in endomembrane organization. It is suggested that it is a dual-function protein that is responsible for actin organization and the synthesis of cell wall materials.
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Genomic context

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See MUR3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
1
Sequence:
Chromosome: 2; NC_003071.7 (8791939..8794401)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene NAD(P)-binding Rossmann-fold superfamily protein Neighboring gene uncharacterized protein Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene cytochrome oxidase complex assembly protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A bi-functional xyloglucan galactosyltransferase is an indispensable salt stress tolerance determinant in Arabidopsis. Li W, et al. Mol Plant, 2013 Jul. PMID 23571490
  2. Characterization of Arabidopsis mur3 mutations that result in constitutive activation of defence in petioles, but not leaves. Tedman-Jones JD, et al. Plant J, 2008 Dec. PMID 18657237
  3. The MUR3 gene of Arabidopsis encodes a xyloglucan galactosyltransferase that is evolutionarily related to animal exostosins. Madson M, et al. Plant Cell, 2003 Jul. PMID 12837954, Free PMC Article
  4. Rapid structural phenotyping of plant cell wall mutants by enzymatic oligosaccharide fingerprinting. Lerouxel O, et al. Plant Physiol, 2002 Dec. PMID 12481058, Free PMC Article
  5. KATAMARI1/MURUS3 Is a novel golgi membrane protein that is required for endomembrane organization in Arabidopsis. Tamura K, et al. Plant Cell, 2005 Jun. PMID 15863516, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Normal growth was restored in the mur3-3 mutant overexpressing XLT2 and in mur3-3 xxt double mutants when the dysfunctional xyloglucan was modified by doubling the amounts of galactosylated side chains.
    Title: Galactose-depleted xyloglucan is dysfunctional and leads to dwarfism in Arabidopsis.
  2. RSA3/MUR3/KAM1 along with other cell wall-associated proteins plays a critical role in salt stress tolerance
    Title: A bi-functional xyloglucan galactosyltransferase is an indispensable salt stress tolerance determinant in Arabidopsis.
  3. Mur3 knockout mutants upregulate defense-related genes, increase production of salicylic acid and reactive oxygen intermediates, and can resist fungal infection in petioles.
    Title: Characterization of Arabidopsis mur3 mutations that result in constitutive activation of defence in petioles, but not leaves.
  4. KAM1/MUR3 is a novel component of the Golgi-mediated organization of actin functioning in proper endomembrane organization and cell elongation.[MUR3] [KAM1]
    Title: KATAMARI1/MURUS3 Is a novel golgi membrane protein that is required for endomembrane organization in Arabidopsis.
Submit: New GeneRIF Correction

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

NM_127596.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables glycosyltransferase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within endomembrane system organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within fucose biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within salicylic acid mediated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within unidimensional cell growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within xyloglucan biosynthetic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus HDA PubMed 
located_in Golgi apparatus ISM
Inferred from Sequence Model
more info
  
located_in Golgi membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in Golgi trans cisterna HDA PubMed 
located_in endosome HDA PubMed 
located_in trans-Golgi network HDA PubMed 

General protein information

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Preferred Names
Exostosin family protein
NP_179627.2
  • MURUS 3 (MUR3); CONTAINS InterPro DOMAIN/s: Exostosin-like (InterPro:IPR004263); BEST Arabidopsis thaliana protein match is: Exostosin family protein (TAIR:AT2G29040.1); Has 481 Blast hits to 480 proteins in 27 species: Archae - 0; Bacteria - 0; Metazoa - 8; Fungi - 4; Plants - 455; Viruses - 0; Other Eukaryotes - 14 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    8791939..8794401
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127596.3 → NP_179627.2  Exostosin family protein [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179627.2

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q0WWH9, Q494P2, Q7XJ98, Q9SK65, W8QNZ0
    UniProtKB/TrEMBL
    A0A178VTY1, A0A5S9WZW3, A0A654EUJ0
    Conserved Domains (1) summary
    pfam03016
    Location:150 → 489
    Exostosin; Exostosin family
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7XJ98.1

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