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FRK1 FLG22-induced receptor-like kinase 1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 816436, updated on 18-Sep-2024

Summary

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Official Symbol
FRK1
Official Full Name
FLG22-induced receptor-like kinase 1
Primary source
TAIR:AT2G19190
Locus tag
AT2G19190
See related
Araport:AT2G19190
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
FLG22-induced receptor-like kinase 1; T20K24.21; T20K24_21
Summary
Receptor-like protein kinase. Involved in early defense signaling.
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Genomic context

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See FRK1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
13
Sequence:
Chromosome: 2; NC_003071.7 (8326049..8329944, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Pectin lyase-like superfamily protein Neighboring gene Core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein Neighboring gene subtilisin-like serine protease 3 Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene miscRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A re-elicitation assay to correlate flg22-signaling competency with ligand-induced endocytic degradation of the FLS2 receptor. Leslie ME, et al. Methods Mol Biol, 2014. PMID 25117282
  2. Submergence confers immunity mediated by the WRKY22 transcription factor in Arabidopsis. Hsu FC, et al. Plant Cell, 2013 Jul. PMID 23897923, Free PMC Article
  3. Specific bacterial suppressors of MAMP signaling upstream of MAPKKK in Arabidopsis innate immunity. He P, et al. Cell, 2006 May 5. PMID 16678099
  4. A membrane protein/signaling protein interaction network for Arabidopsis version AMPv2. Lalonde S, et al. Front Physiol, 2010. PMID 21423366, Free PMC Article
  5. An extracellular network of Arabidopsis leucine-rich repeat receptor kinases. Smakowska-Luzan E, et al. Nature, 2018 Jan 18. PMID 29320478, Free PMC Article

See all (8) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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NM_127476.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables kinase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within defense response to bacterium IDA
Inferred from Direct Assay
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  

General protein information

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Preferred Names
FLG22-induced receptor-like kinase 1
NP_179509.1
  • FLG22-induced receptor-like kinase 1 (FRK1); FUNCTIONS IN: kinase activity; INVOLVED IN: defense response to bacterium; LOCATED IN: endomembrane system; EXPRESSED IN: stem, sepal, stamen; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), Leucine-rich repeat (InterPro:IPR001611), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635); BEST Arabidopsis thaliana protein match is: Leucine-rich repeat transmembrane protein kinase protein (TAIR:AT4G29990.1); Has 158999 Blast hits to 129792 proteins in 4951 species: Archae - 135; Bacteria - 15029; Metazoa - 47296; Fungi - 11032; Plants - 64935; Viruses - 473; Other Eukaryotes - 20099 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    8326049..8329944 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127476.2 → NP_179509.1  FLG22-induced receptor-like kinase 1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179509.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O64483
    UniProtKB/TrEMBL
    A0A5S9WZI5, C0LGK5
    Conserved Domains (4) summary
    smart00221
    Location:576 → 839
    STYKc; Protein kinase; unclassified specificity
    cd14066
    Location:580 → 845
    STKc_IRAK; Catalytic domain of the Serine/Threonine kinases, Interleukin-1 Receptor Associated Kinases and related STKs
    sd00033
    Location:396 → 415
    LRR_RI; leucine-rich repeat [structural motif]
    pfam12819
    Location:33 → 358
    Malectin_like; Carbohydrate-binding protein of the ER
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O64483.1

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