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SRP2 serpin 2 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 815941, updated on 18-Sep-2024

Summary

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Official Symbol
SRP2
Official Full Name
serpin 2
Primary source
TAIR:AT2G14540
Locus tag
AT2G14540
See related
Araport:AT2G14540
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
ATSRP2; serpin 2; T13P21.8; T13P21_8
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Genomic context

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See SRP2 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
2
Sequence:
Chromosome: 2; NC_003071.7 (6197663..6199406, complement)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene miscRNA Neighboring gene ncRNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Serpin genes AtSRP2 and AtSRP3 are required for normal growth sensitivity to a DNA alkylating agent in Arabidopsis. Ahn JW, et al. BMC Plant Biol, 2009 May 11. PMID 19426562, Free PMC Article
  2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Expression of serpins AtSRP2 and AtSRP3 is required for normal responses of plants following exposure to alkylating genotoxins.
    Title: Serpin genes AtSRP2 and AtSRP3 are required for normal growth sensitivity to a DNA alkylating agent in Arabidopsis.
Submit: New GeneRIF Correction

General gene information

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NM_127017.2

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA damage response IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within DNA repair IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region ISM
Inferred from Sequence Model
more info
  
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
serpin 2
NP_179060.1
  • serpin 2 (SRP2); FUNCTIONS IN: serine-type endopeptidase inhibitor activity; INVOLVED IN: DNA repair, response to DNA damage stimulus; LOCATED IN: nucleus; EXPRESSED IN: fruit; CONTAINS InterPro DOMAIN/s: Protease inhibitor I4, serpin, plant (InterPro:IPR015554), Protease inhibitor I4, serpin (InterPro:IPR000215); BEST Arabidopsis thaliana protein match is: Serine protease inhibitor (SERPIN) family protein (TAIR:AT1G62170.1); Has 6246 Blast hits to 6203 proteins in 468 species: Archae - 66; Bacteria - 371; Metazoa - 4782; Fungi - 10; Plants - 340; Viruses - 461; Other Eukaryotes - 216 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    6197663..6199406 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_127017.2 → NP_179060.1  serpin 2 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_179060.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9ZQR6
    UniProtKB/TrEMBL
    A0A178W286, A0A5S9WY36
    Conserved Domains (1) summary
    cl00137
    Location:36 → 397
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9ZQR6.1

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