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stom stomatin [ Danio rerio (zebrafish) ]

Gene ID: 81534, updated on 9-Dec-2024

Summary

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Official Symbol
stomprovided by ZNC
Official Full Name
stomatinprovided by ZNC
Primary source
ZFIN:ZDB-GENE-980526-486
See related
Ensembl:ENSDARG00000003835 AllianceGenome:ZFIN:ZDB-GENE-980526-486
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
epb72; band72; band7.2; zgc:110814
Summary
Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human STOM (stomatin). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
human mouse all
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Genomic context

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See stom in Genome Data Viewer
Location:
chromosome: 21
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (17542473..17570220)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (17505805..17533584)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene general transcription factor IIIC, polypeptide 4 Neighboring gene BarH-like homeobox 1b Neighboring gene gelsolin a Neighboring gene retinoid X receptor, alpha a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Vertebrate genome evolution and the zebrafish gene map. Postlethwait JH, et al. Nat Genet, 1998 Apr. PMID 9537416
  2. Gene duplication, conservation, and divergence of activating transcription factor 5 gene in zebrafish. Zhu H, et al. J Exp Zool B Mol Dev Evol, 2022 Jul. PMID 35226401
  3. A genetic linkage map for zebrafish: comparative analysis and localization of genes and expressed sequences. Gates MA, et al. Genome Res, 1999 Apr. PMID 10207156
  4. Many genes in fish have species-specific asymmetric rates of molecular evolution. Steinke D, et al. BMC Genomics, 2006 Feb 8. PMID 16466575, Free PMC Article
  5. A Toolbox for Efficient Proximity-Dependent Biotinylation in Zebrafish Embryos. Rosenthal SM, et al. Mol Cell Proteomics, 2021. PMID 34332124, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
stomatin
Names
erythrocyte protein band 7.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001320073.1 → NP_001307002.1  stomatin isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    CR762400
    UniProtKB/TrEMBL
    A0A8M1P7K2, F1QCQ7
    Related
    ENSDARP00000120230.1, ENSDART00000141326.2
    Conserved Domains (2) summary
    smart00244
    Location:64 → 216
    PHB; prohibitin homologues
    cd03403
    Location:85 → 286
    SPFH_stomatin; Stomatin, a subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

  2. NM_131758.2 → NP_571833.1  stomatin isoform 2

    See identical proteins and their annotated locations for NP_571833.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
    Source sequence(s)
    CR762400
    UniProtKB/TrEMBL
    A0A8N7UZM9, O93423
    Related
    ENSDARP00000010282.4, ENSDART00000005750.6
    Conserved Domains (2) summary
    smart00244
    Location:54 → 206
    PHB; prohibitin homologues
    cd03403
    Location:75 → 276
    SPFH_stomatin; Stomatin, a subgroup of the stomatin-like proteins (slipins) family; belonging to the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    17542473..17570220
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017352833.3 → XP_017208322.1  stomatin isoform X1

    UniProtKB/TrEMBL
    A0A0R4IGK4, A0A8M6Z3Q4
    Related
    ENSDARP00000133615.1, ENSDART00000163238.3

  2. XM_017352834.3 → XP_017208323.1  stomatin isoform X2

    UniProtKB/TrEMBL
    A0A2R8RTR5, A0A8M6YUJ4
    Related
    ENSDARP00000152629.1, ENSDART00000191700.1

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018395085.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    262258..289474
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_2

Genomic

  1. NW_018395347.1 Reference GRCz11 ALT_DRER_TU_2

    Range
    32544..60291
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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