U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SPR1 spiral1 [ Arabidopsis thaliana (thale cress) ]

Gene ID: 814896, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
SPR1
Official Full Name
spiral1
Primary source
TAIR:AT2G03680
Locus tag
AT2G03680
See related
Araport:AT2G03680
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Arabidopsis thaliana (ecotype: Columbia)
Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as
F19B11.13; F19B11_13; SKU6; SPIRAL1
Summary
The SPR1 gene encodes a plant-specific 12-kD protein which has a repeated motif at both ends, separated by a predicted rod-like domain, suggesting that it may act as an intermolecular linker. Ubiquitously expressed and belongs to a six-member gene family in Arabidopsis; expressed in transgenic seedlings localized to microtubules within the cortical array, preprophase band, phragmoplast, and mitotic spindle.
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See SPR1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
3
Sequence:
Chromosome: 2; NC_003071.7 (1120787..1122055)

Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Asparagine synthase family protein Neighboring gene cell division cycle 48B Neighboring gene ncRNA Neighboring gene coenzyme Q biosynthesis Coq4 family protein / ubiquinone biosynthesis Coq4 family protein Neighboring gene ncRNA Neighboring gene tRNA-Thr

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NC_003071.7

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Salt stress-induced disassembly of Arabidopsis cortical microtubule arrays involves 26S proteasome-dependent degradation of SPIRAL1. Wang S, et al. Plant Cell, 2011 Sep. PMID 21954463, Free PMC Article
  2. Role of the SPIRAL1 gene family in anisotropic growth of Arabidopsis thaliana. Nakajima K, et al. Plant Cell Physiol, 2006 Apr. PMID 16478750
  3. The Arabidopsis sku6/spiral1 gene encodes a plus end-localized microtubule-interacting protein involved in directional cell expansion. Sedbrook JC, et al. Plant Cell, 2004 Jun. PMID 15155883, Free PMC Article
  4. The OPEN STOMATA1-SPIRAL1 module regulates microtubule stability during abscisic acid-induced stomatal closure in Arabidopsis. Wang P, et al. Plant Cell, 2023 Jan 2. PMID 36255272, Free PMC Article
  5. The SPIRAL genes are required for directional control of cell elongation in Aarabidopsis thaliana. Furutani I, et al. Development, 2000 Oct. PMID 11003843

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The OPEN STOMATA1-SPIRAL1 module regulates microtubule stability during abscisic acid-induced stomatal closure in Arabidopsis.
    Title: The OPEN STOMATA1-SPIRAL1 module regulates microtubule stability during abscisic acid-induced stomatal closure in Arabidopsis.
  2. SPR1 and EB1b have complex interactions as they load onto microtubule plus ends and direct polar cell expansion and organ growth in response to directional cues.
    Title: The microtubule plus-end tracking proteins SPR1 and EB1b interact to maintain polar cell elongation and directional organ growth in Arabidopsis.
  3. Salt stress accelerates the 26S proteasome-dependent degradation of SPR1 and facilitates microtubule disassembly and promotes salt stress tolerance.
    Title: Salt stress-induced disassembly of Arabidopsis cortical microtubule arrays involves 26S proteasome-dependent degradation of SPIRAL1.
  4. these observations suggest that SPR1 and SP1Ls act redundantly in maintaining the cortical microtubule organization essential for anisotropic cell growth
    Title: Role of the SPIRAL1 gene family in anisotropic growth of Arabidopsis thaliana.
  5. Observations suggest that SPR1 is involved in microtubule polymerization dynamics and/or guidance, which in turn influences touch-induced directional cell expansion and axial twisting. [SPIRAL1]
    Title: The Arabidopsis sku6/spiral1 gene encodes a plus end-localized microtubule-interacting protein involved in directional cell expansion.
Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

NM_001161019.2
NM_001335199.1
NM_126416.3

Gene Ontology Provided by TAIR

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within anisotropic cell growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within cellular response to salt stress IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within cortical microtubule organization IGI
Inferred from Genetic Interaction
more info
 PubMed 
acts_upstream_of_or_within unidimensional cell growth IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
colocalizes_with cortical microtubule IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cortical microtubule, transverse to long axis IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol HDA PubMed 
located_in mitochondrion HDA PubMed 
located_in phragmoplast IDA
Inferred from Direct Assay
more info
 PubMed 
located_in preprophase band IDA
Inferred from Direct Assay
more info
 PubMed 
located_in spindle microtubule IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
spiral1
NP_001154491.1
  • SPIRAL1 (SPR1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: anisotropic cell growth, unidimensional cell growth; LOCATED IN: spindle microtubule, cortical microtubule, transverse to long axis, preprophase band, phragmoplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; BEST Arabidopsis thaliana protein match is: SPIRAL1-like2 (TAIR:AT1G69230.2); Has 191 Blast hits to 165 proteins in 37 species: Archae - 0; Bacteria - 8; Metazoa - 3; Fungi - 6; Plants - 146; Viruses - 0; Other Eukaryotes - 28 (source: NCBI BLink).
NP_178464.1
  • SPIRAL1 (SPR1); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: anisotropic cell growth, unidimensional cell growth; LOCATED IN: spindle microtubule, cortical microtubule, transverse to long axis, preprophase band, phragmoplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; BEST Arabidopsis thaliana protein match is: SPIRAL1-like2 (TAIR:AT1G69230.2); Has 191 Blast hits to 165 proteins in 37 species: Archae - 0; Bacteria - 8; Metazoa - 3; Fungi - 6; Plants - 146; Viruses - 0; Other Eukaryotes - 28 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003071.7 Reference assembly

    Range
    1120787..1122055
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_126416.3 → NP_178464.1  spiral1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_178464.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O49622, Q9SJW3
    UniProtKB/TrEMBL
    A0A178W0C9, A0A5S9WWX9

  2. NM_001335199.1 → NP_001323957.1  spiral1 [Arabidopsis thaliana]

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O49622, Q9SJW3
    UniProtKB/TrEMBL
    A0A178W0C9, A0A5S9WWX9

  3. NM_001161019.2 → NP_001154491.1  spiral1 [Arabidopsis thaliana]

    See identical proteins and their annotated locations for NP_001154491.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    O49622, Q9SJW3
    UniProtKB/TrEMBL
    A0A178W0C9, A0A5S9WWX9
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9SJW3.1

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools