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itk - IL2 inducible T cell kinase

Predicted to enable non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in NK T cell differentiation; adaptive immune response; and antigen receptor-mediated signaling pathway. Predicted to act upstream of or within immune system process; intracellular signal transduction; and protein phosphorylation. Predicted to be located in cytosol. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in lymphoproliferative syndrome 1. Orthologous to human ITK (IL2 inducible T cell kinase). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa