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ZNF768 zinc finger protein 768 [ Homo sapiens (human) ]

Gene ID: 79724, updated on 27-Nov-2024

Summary

Official Symbol
ZNF768provided by HGNC
Official Full Name
zinc finger protein 768provided by HGNC
Primary source
HGNC:HGNC:26273
See related
Ensembl:ENSG00000169957 MIM:618032; AllianceGenome:HGNC:26273
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in chromosome. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in testis (RPKM 9.9), kidney (RPKM 9.1) and 25 other tissues See more
Orthologs
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Genomic context

See ZNF768 in Genome Data Viewer
Location:
16p11.2
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (30524004..30532477, complement)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (30910973..30919446, complement)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (30535325..30537887, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene integrin subunit alpha L Neighboring gene ITGAL antisense RNA 1 Neighboring gene microRNA 4518 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10708 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7375 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7376 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7377 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10709 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr16:30544613-30545124 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 10710 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 7378 Neighboring gene Sharpr-MPRA regulatory region 7881 Neighboring gene zinc finger protein 747 Neighboring gene ZNF747 divergent transcript Neighboring gene RPL7L1 pseudogene 16 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr16:30552221-30552866 Neighboring gene uncharacterized LOC124903677 Neighboring gene Sharpr-MPRA regulatory region 8694

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ23436

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024671.4NP_078947.3  zinc finger protein 768

    See identical proteins and their annotated locations for NP_078947.3

    Status: VALIDATED

    Source sequence(s)
    BC013760, BQ635980
    Consensus CDS
    CCDS10681.2
    UniProtKB/Swiss-Prot
    Q569L7, Q96CX4, Q9H5H4
    Related
    ENSP00000369777.5, ENST00000380412.7
    Conserved Domains (4) summary
    COG5048
    Location:276504
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:459479
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:513535
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:331354
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    30524004..30532477 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017023666.2XP_016879155.1  zinc finger protein 768 isoform X2

    UniProtKB/TrEMBL
    H3BS42
    Related
    ENSP00000456527.1, ENST00000562803.1
  2. XM_017023665.3XP_016879154.1  zinc finger protein 768 isoform X1

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    30910973..30919446 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054313932.1XP_054169907.1  zinc finger protein 768 isoform X2

  2. XM_054313931.1XP_054169906.1  zinc finger protein 768 isoform X1