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nexmifb neurite extension and migration factor b [ Danio rerio (zebrafish) ]

Gene ID: 796115, updated on 4-Jan-2025

Summary

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Official Symbol
nexmifbprovided by ZNC
Official Full Name
neurite extension and migration factor bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-140106-18
See related
Ensembl:ENSDARG00000029296 AllianceGenome:ZFIN:ZDB-GENE-140106-18
Gene type
protein coding
RefSeq status
MODEL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
kiaa2022; gb:eb776709; si:ch211-134n22.1
Summary
Predicted to be involved in negative regulation of cell adhesion and negative regulation of neuron migration. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 98. Orthologous to human NEXMIF (neurite extension and migration factor). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
human mouse all
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Genomic context

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See nexmifb in Genome Data Viewer
Location:
chromosome: 14
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 14 NC_007125.7 (11103710..11268376)
105 previous assembly GRCz10 (GCF_000002035.5) 14 NC_007125.6 (10797710..10959438)

Chromosome 14 - NC_007125.7Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 15b Neighboring gene ATP-binding cassette, sub-family B (MDR/TAP), member 7 Neighboring gene MAP7 domain-containing protein 1-like Neighboring gene ring finger protein, LIM domain interacting

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by ZFIN

Process Evidence Code Pubs
involved_in negative regulation of cell adhesion mediated by integrin IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of cell-cell adhesion mediated by cadherin IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of cell-matrix adhesion IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in negative regulation of neuron migration IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
neurite extension and migration factor
Names
zmp:0000001058

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007125.7 Reference GRCz11 Primary Assembly

    Range
    11103710..11268376
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005157176.5 → XP_005157233.1  neurite extension and migration factor

    See identical proteins and their annotated locations for XP_005157233.1

    UniProtKB/TrEMBL
    A0A8M2B3C0, F1QPA3
    Related
    ENSDARP00000136265.1, ENSDART00000161311.2
    Conserved Domains (1) summary
    pfam15735
    Location:158 → 485
    DUF4683; Domain of unknown function (DUF4683)

  2. XM_009307766.4 → XP_009306041.1  neurite extension and migration factor

    See identical proteins and their annotated locations for XP_009306041.1

    UniProtKB/TrEMBL
    A0A8M2B3C0, F1QPA3
    Conserved Domains (1) summary
    pfam15735
    Location:158 → 485
    DUF4683; Domain of unknown function (DUF4683)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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