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krt4 - keratin 4

Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be located in intermediate filament. Predicted to be active in keratin filament. Is expressed in several structures, including digestive system; ectoderm; endocrine system; head; and integument. Human ortholog(s) of this gene implicated in several diseases, including Meesmann corneal dystrophy 2; autosomal dominant woolly hair; hypotrichosis (multiple); ichthyosis (multiple); and palmoplantar keratosis (multiple). Orthologous to several human genes including KRT8 (keratin 8). [provided by Alliance of Genome Resources, Nov 2024]

Genes similar to krt4

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Species Gene Architecture aa