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gfra1a - gdnf family receptor alpha 1a

Enables MAP kinase kinase kinase activity. Acts upstream of or within enteric nervous system development and protein-containing complex assembly. Predicted to be located in plasma membrane and side of membrane. Predicted to be part of receptor complex. Predicted to be active in external side of plasma membrane. Is expressed in germ line cell; nervous system; pleuroperitoneal region; presumptive enteric nervous system; and vagal neural crest. Human ortholog(s) of this gene implicated in renal agenesis. Orthologous to human GFRA1 (GDNF family receptor alpha 1). [provided by Alliance of Genome Resources, Nov 2024]

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Species Gene Architecture aa