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irf1b - interferon regulatory factor 1b

Enables transcription cis-regulatory region binding activity. Acts upstream of or within regulation of defense response to virus and response to virus. Located in nucleus. Is expressed in several structures, including cardiovascular system; eye; liver; pleuroperitoneal region; and thymus. Human ortholog(s) of this gene implicated in asthma; lung cancer (multiple); primary immunodeficiency disease; smallpox; and stomach cancer (multiple). Orthologous to human IRF1 (interferon regulatory factor 1). [provided by Alliance of Genome Resources, Dec 2024]

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Species Gene Architecture aa