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wnt4b wingless-type MMTV integration site family, member 4b [ Danio rerio (zebrafish) ]

Gene ID: 791993, updated on 4-Jan-2025

Summary

Official Symbol
wnt4bprovided by ZNC
Official Full Name
wingless-type MMTV integration site family, member 4bprovided by ZNC
Primary source
ZFIN:ZDB-GENE-000411-1
See related
Ensembl:ENSDARG00000040159 AllianceGenome:ZFIN:ZDB-GENE-000411-1
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary
Predicted to enable cytokine activity and frizzled binding activity. Acts upstream of or within negative regulation of mitotic nuclear division. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in blastomere and nervous system. [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See wnt4b in Genome Data Viewer
Location:
chromosome: 16
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (31802203..31813018)
105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (31846615..31857430)

Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase non-receptor type 6 Neighboring gene chromodomain helicase DNA binding protein 4b Neighboring gene cell division cycle 42, like Neighboring gene myeloid leukemia factor 2

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Pathways from PubChem

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables cytokine activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables frizzled binding IBA
Inferred from Biological aspect of Ancestor
more info
 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
 
involved_in canonical Wnt signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cell fate commitment IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within negative regulation of mitotic nuclear division IMP
Inferred from Mutant Phenotype
more info
 
involved_in neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of mitotic nuclear division IGI
Inferred from Genetic Interaction
more info
 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
wingless-type MMTV integration site family, member 4b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_131500.2NP_571575.2  wingless-type MMTV integration site family, member 4b

    Status: VALIDATED

    Source sequence(s)
    BX511250
    UniProtKB/TrEMBL
    Q9IAU3
    Related
    ENSDARP00000058738.5, ENSDART00000058739.5

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007127.7 Reference GRCz11 Primary Assembly

    Range
    31802203..31813018
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCz11 ALT_DRER_TU_1

Genomic

  1. NW_018394963.1 Reference GRCz11 ALT_DRER_TU_1

    Range
    65485..76273
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)