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ecrg4a ECRG4 augurin precursor a [ Danio rerio (zebrafish) ]

Gene ID: 791762, updated on 2-Nov-2024

Summary

Official Symbol
ecrg4aprovided by ZNC
Official Full Name
ECRG4 augurin precursor aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-050417-189
See related
Ensembl:ENSDARG00000056087 AllianceGenome:ZFIN:ZDB-GENE-050417-189
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:112443
Summary
Acts upstream of or within central nervous system development and regulation of cell population proliferation. Predicted to be located in apical plasma membrane and cytoplasm. Predicted to be active in extracellular space. Is expressed in epidermis; pectoral fin; and pharyngeal arch. Orthologous to human ECRG4 (ECRG4 augurin precursor). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See ecrg4a in Genome Data Viewer
Location:
chromosome: 9
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (6371919..6380653, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (6393934..6402668, complement)

Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene ST6 beta-galactosamide alpha-2,6-sialyltranferase 2a Neighboring gene teleost multiple tissue opsin 2b Neighboring gene UDP-glucuronate decarboxylase 1 Neighboring gene NCK adaptor protein 2a Neighboring gene uncharacterized LOC137496441

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Markers

Clone Names

  • MGC112443

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in G1 to G0 transition IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in anaphase-promoting complex-dependent catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in cellular senescence IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in central nervous system development IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within central nervous system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in negative regulation of cell population proliferation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in regulation of cell population proliferation IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within regulation of cell population proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in response to wounding ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in extracellular space ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
augurin-A
Names
esophageal cancer related gene 4a
esophageal cancer-related gene 4
esophageal cancer-related gene 4-A protein homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001017697.1NP_001017697.1  augurin-A precursor

    See identical proteins and their annotated locations for NP_001017697.1

    Status: PROVISIONAL

    Source sequence(s)
    BC093311
    UniProtKB/Swiss-Prot
    F1R4S5, Q566V9
    Related
    ENSDARP00000072984.3, ENSDART00000078523.5
    Conserved Domains (1) summary
    pfam15187
    Location:29142
    Augurin; Oesophageal cancer-related gene 4

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007120.7 Reference GRCz11 Primary Assembly

    Range
    6371919..6380653 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)