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slc26a1 solute carrier family 26 member 1 [ Danio rerio (zebrafish) ]

Gene ID: 791185, updated on 9-Dec-2024

Summary

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Official Symbol
slc26a1provided by ZNC
Official Full Name
solute carrier family 26 member 1provided by ZNC
Primary source
ZFIN:ZDB-GENE-070112-2182
See related
Ensembl:ENSDARG00000029832 AllianceGenome:ZFIN:ZDB-GENE-070112-2182
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
sb:cb565; wu:fe23c03; zgc:158435
Summary
Predicted to enable inorganic anion transmembrane transporter activity and organic anion transmembrane transporter activity. Predicted to be involved in chloride transmembrane transport and sulfate transmembrane transport. Predicted to act upstream of or within monoatomic ion transport and transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in external yolk syncytial layer; pronephric duct; pronephric proximal convoluted tubule; and yolk syncytial layer. Human ortholog(s) of this gene implicated in calcium oxalate nephrolithiasis. Orthologous to human SLC26A1 (solute carrier family 26 member 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See slc26a1 in Genome Data Viewer
Location:
chromosome: 21
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (20324562..20332584, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (20287926..20295924, complement)

Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene si:dkey-247m21.3 Neighboring gene zgc:86764 Neighboring gene uncharacterized LOC101886495 Neighboring gene retinol binding protein 4, like Neighboring gene phosphodiesterase 6B, cGMP-specific, rod, beta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Androgen receptor gene expression in the developing and adult zebrafish brain. Gorelick DA, et al. Dev Dyn, 2008 Oct. PMID 18816841
  2. Single-cell mRNA profiling reveals changes in solute carrier expression and suggests a metabolic switch during zebrafish pronephros development. Schoels M, et al. Am J Physiol Renal Physiol, 2021 May 1. PMID 33749326
  3. Evi1 is specifically expressed in the distal tubule and duct of the Xenopus pronephros and plays a role in its formation. Van Campenhout C, et al. Dev Biol, 2006 Jun 1. PMID 16574097
  4. The involvement of SLC26 anion transporters in chloride uptake in zebrafish (Danio rerio) larvae. Bayaa M, et al. J Exp Biol, 2009 Oct. PMID 19801433
  5. The primary role of zebrafish nanog is in extra-embryonic tissue. Gagnon JA, et al. Development, 2018 Jan 9. PMID 29180571, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
  
enables bicarbonate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables chloride transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables oxalate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables secondary active sulfate transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables sulfate transmembrane transporter activity IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in chloride transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sulfate transmembrane transport IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
sulfate anion transporter 1
Names
Sat1
solute carrier family 26 (anion exchanger), member 1
solute carrier family 26 (sulfate transporter), member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080667.2 → NP_001074136.2  sulfate anion transporter 1

    Status: VALIDATED

    Source sequence(s)
    AL844141, BX511179
    UniProtKB/TrEMBL
    A0A0R4IDN4, A0A8M3ATV7, A1L1V8
    Related
    ENSDARP00000131271.1, ENSDART00000166049.2

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007132.7 Reference GRCz11 Primary Assembly

    Range
    20324562..20332584 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009295333.4 → XP_009293608.1  sulfate anion transporter 1 isoform X1

    See identical proteins and their annotated locations for XP_009293608.1

    UniProtKB/TrEMBL
    A0A0R4IDN4, A0A8M3ATV7, A1L1V8
    Conserved Domains (2) summary
    cd07042
    Location:542 → 691
    STAS_SulP_like_sulfate_transporter; Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function
    TIGR00815
    Location:59 → 695
    sulP; high affinity sulphate transporter 1
Nucleotide Protein Strain
Heading Accession and Version

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