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rabep2 rabaptin, RAB GTPase binding effector protein 2 [ Danio rerio (zebrafish) ]

Gene ID: 791143, updated on 9-Dec-2024

Summary

Official Symbol
rabep2provided by ZNC
Official Full Name
rabaptin, RAB GTPase binding effector protein 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-070112-572
See related
Ensembl:ENSDARG00000061213 AllianceGenome:ZFIN:ZDB-GENE-070112-572
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:158419
Summary
Predicted to enable GTPase activator activity and growth factor activity. Predicted to act upstream of or within endocytosis and protein transport. Predicted to be located in early endosome. Predicted to be active in intracellular membrane-bounded organelle. Orthologous to human RABEP2 (rabaptin, RAB GTPase binding effector protein 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See rabep2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (26157722..26171558, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (26026851..26040687, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC137490006 Neighboring gene uncharacterized LOC103910249 Neighboring gene ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 Neighboring gene si:ch211-11k18.4 Neighboring gene yippee-like 3

Genomic regions, transcripts, and products

Expression

  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

General gene information

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 
enables growth factor activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within endocytosis IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in early endosome IEA
Inferred from Electronic Annotation
more info
 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
is_active_in intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
rab GTPase-binding effector protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080625.2NP_001074094.2  rab GTPase-binding effector protein 2

    Status: VALIDATED

    Source sequence(s)
    CF265814, FP016243
    UniProtKB/TrEMBL
    A0A8M1NCV5, F1Q793
    Related
    ENSDARP00000103396.3, ENSDART00000113890.5
    Conserved Domains (3) summary
    pfam08172
    Location:371405
    CASP_C; CASP C terminal
    pfam09311
    Location:221460
    Rab5-bind; Rabaptin-like protein
    cl01825
    Location:4192
    Phage_Mu_Gam; Bacteriophage Mu Gam like protein

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    26157722..26171558 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)