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CARD14 caspase recruitment domain family member 14 [ Homo sapiens (human) ]

Gene ID: 79092, updated on 27-Nov-2024

Summary

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Official Symbol
CARD14provided by HGNC
Official Full Name
caspase recruitment domain family member 14provided by HGNC
Primary source
HGNC:HGNC:16446
See related
Ensembl:ENSG00000141527 MIM:607211; AllianceGenome:HGNC:16446
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PRP; PSS1; BIMP2; CARMA2; PSORS2
Summary
This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]
Expression
Broad expression in skin (RPKM 4.8), adrenal (RPKM 1.8) and 21 other tissues See more
Orthologs
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Genomic context

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See CARD14 in Genome Data Viewer
Location:
17q25.3
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (80170030..80209331)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (81070412..81109756)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (78143829..78183130)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9099 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12928 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78083610-78084585 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:78086615-78087127 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78091523-78092024 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:78097302-78097924 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:78107357-78107522 Neighboring gene alpha glucosidase Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:78120154-78120868 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:78120869-78121581 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:78121582-78122295 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78122296-78123008 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:78126203-78126704 Neighboring gene H3K27ac hESC enhancer GRCh37_chr17:78126705-78127204 Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr17:78129355-78129892 Neighboring gene eukaryotic translation initiation factor 4A3 Neighboring gene Sharpr-MPRA regulatory region 5287 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr17:78151904-78153103 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:78163065-78163581 Neighboring gene MED14-independent group 3 enhancer GRCh37_chr17:78178385-78179584 Neighboring gene ReSE screen-validated silencer GRCh37_chr17:78183891-78184046 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12929 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9102 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9103 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78195951-78196788 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78196789-78197626 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78200105-78200606 Neighboring gene N-sulfoglucosamine sulfohydrolase Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78209849-78210638 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78210639-78211426 Neighboring gene solute carrier family 26 member 11 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:78227308-78228024 Neighboring gene SLC26A11-RNF213 intergenic CAGE-defined mid-level expression enhancer Neighboring gene CRISPRi-validated cis-regulatory element chr17.5742 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9104 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9105 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9106 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr17:78237270-78237826 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12933 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 12934 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 9107 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78247837-78248435 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78251821-78252439 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78258533-78259093 Neighboring gene ring finger protein 213 Neighboring gene RNF213 antisense RNA 1 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr17:78345568-78346767 Neighboring gene MPRA-validated peak3024 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78354122-78354622 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr17:78359110-78360309 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78369069-78369570 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78371216-78371723 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr17:78371724-78372230

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Variant analysis of CARD14 in a Chinese Han population with psoriasis vulgaris and generalized pustular psoriasis. Qin P, et al. J Invest Dermatol, 2014 Dec. PMID 24999592, Free PMC Article
  2. Loss-of-function mutations in caspase recruitment domain-containing protein 14 (CARD14) are associated with a severe variant of atopic dermatitis. Peled A, et al. J Allergy Clin Immunol, 2019 Jan. PMID 30248356
  3. CARD14-associated papulosquamous eruption: A spectrum including features of psoriasis and pityriasis rubra pilaris. Craiglow BG, et al. J Am Acad Dermatol, 2018 Sep. PMID 29477734, Free PMC Article
  4. Beneficial effect of ustekinumab in familial pityriasis rubra pilaris with a new missense mutation in CARD14. Lwin SM, et al. Br J Dermatol, 2018 Apr. PMID 28301045
  5. Pityriasis Rubra Pilaris Type V as an Autoinflammatory Disease by CARD14 Mutations. Takeichi T, et al. JAMA Dermatol, 2017 Jan 1. PMID 27760266

See all (82) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease.
    Title: Regulation of MYC by CARD14 in human epithelium is a determinant of epidermal homeostasis and disease.
  2. Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in keratinocytes.
    Title: Polo-like kinase 1 (PLK1) is a novel CARD14-binding protein in keratinocytes.
  3. A novel mutation in a CARD14-associated papulosquamous eruption.
    Title: A novel mutation in a CARD14-associated papulosquamous eruption.
  4. Correlation of IL36RN and CARD14 mutations with clinical manifestations and laboratory findings in patients with generalised pustular psoriasis.
    Title: Correlation of IL36RN and CARD14 mutations with clinical manifestations and laboratory findings in patients with generalised pustular psoriasis.
  5. Damaging Alleles Affecting Multiple CARD14 Domains Are Associated with Palmoplantar Pustulosis.
    Title: Damaging Alleles Affecting Multiple CARD14 Domains Are Associated with Palmoplantar Pustulosis.
  6. Association between CARD14 gene polymorphisms and psoriasis vulgaris in Hainan Han population based on exon sequencing: A case-control study.
    Title: Association between CARD14 gene polymorphisms and psoriasis vulgaris in Hainan Han population based on exon sequencing: A case-control study.
  7. Association of CARD14 Single-Nucleotide Polymorphisms with Psoriasis.
    Title: Association of CARD14 Single-Nucleotide Polymorphisms with Psoriasis.
  8. Novel role for caspase recruitment domain family member 14 and its genetic variant rs11652075 in skin filaggrin homeostasis.
    Title: Novel role for caspase recruitment domain family member 14 and its genetic variant rs11652075 in skin filaggrin homeostasis.
  9. GJB2 mutations in Iranian Azeri population with autosomal recessive nonsyndromic hearing loss (ARNSHL): First report of c.238 C>A mutation in Iran.
    Title: GJB2 mutations in Iranian Azeri population with autosomal recessive nonsyndromic hearing loss (ARNSHL): First report of c.238 C>A mutation in Iran.
  10. CARD14-associated papulosquamous eruption (CAPE) in pediatric patients: Three additional cases and review of the literature.
    Title: CARD14-associated papulosquamous eruption (CAPE) in pediatric patients: Three additional cases and review of the literature.
Submit: New GeneRIF Correction See all GeneRIFs (60)

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Associated conditions

Description Tests
Pityriasis rubra pilaris
MedGen: C0032027 OMIM: 173200 GeneReviews: Not available
Compare labs
Psoriasis 2
MedGen: C1864497 OMIM: 602723 GeneReviews: Not available
Compare labs

Copy number response

Description
Copy number response
Haploinsufficency

No evidence available (Last evaluated 2013-08-01)

ClinGen Genome Curation Page
Triplosensitivity

No evidence available (Last evaluated 2013-08-01)

ClinGen Genome Curation Page

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ38097

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables CARD domain binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of NF-kappaB-inducing kinase activity NAS
Non-traceable Author Statement
more info
 PubMed 
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
  
involved_in negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of NF-kappaB transcription factor activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in positive regulation of protein phosphorylation IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of immune response IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in tumor necrosis factor-mediated signaling pathway IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in aggresome IDA
Inferred from Direct Assay
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IDA
Inferred from Direct Assay
more info
  
located_in plasma membrane NAS
Non-traceable Author Statement
more info
 PubMed 

General protein information

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Preferred Names
caspase recruitment domain-containing protein 14
Names
CARD-containing MAGUK protein 2
bcl10-interacting maguk protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_032778.1 RefSeqGene

    Range
    5039..44340
    Download
    GenBank, FASTA, Sequence Viewer (Graphics), LRG_1330

mRNA and Protein(s)

  1. NM_001257970.1 → NP_001244899.1  caspase recruitment domain-containing protein 14 isoform 3

    See identical proteins and their annotated locations for NP_001244899.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks several exons and its transcription extends past a splice site that is used in variant 1. The encoded isoform 3 has a shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    AC087741, BC018142
    Consensus CDS
    CCDS58605.1
    UniProtKB/TrEMBL
    A0A494C199
    Related
    ENSP00000461806.1, ENST00000570421.5
    Conserved Domains (5) summary
    cd00992
    Location:583 → 655
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08806
    Location:19 → 104
    CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
    pfam15252
    Location:410 → 481
    DUF4589; Domain of unknown function (DUF4589)
    cl17036
    Location:680 → 740
    SH3; Src Homology 3 domain superfamily
    cl25732
    Location:151 → 409
    SMC_N; RecF/RecN/SMC N terminal domain

  2. NM_001366385.1 → NP_001353314.1  caspase recruitment domain-containing protein 14 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AC087741
    Consensus CDS
    CCDS11768.1
    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6
    UniProtKB/TrEMBL
    A0A494C1N2
    Related
    ENSP00000498071.1, ENST00000648509.2
    Conserved Domains (5) summary
    cd00992
    Location:583 → 655
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08806
    Location:19 → 104
    CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
    cl17036
    Location:680 → 742
    SH3; Src Homology 3 domain superfamily
    cl17190
    Location:858 → 961
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    cl25732
    Location:151 → 448
    SMC_N; RecF/RecN/SMC N terminal domain

  3. NM_024110.4 → NP_077015.2  caspase recruitment domain-containing protein 14 isoform 1

    See identical proteins and their annotated locations for NP_077015.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1). Variants 1 and 5 encode the same isoform.
    Source sequence(s)
    AC087741, AF322642, BU617627
    Consensus CDS
    CCDS11768.1
    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6
    UniProtKB/TrEMBL
    A0A494C1N2
    Related
    ENSP00000344549.2, ENST00000344227.6
    Conserved Domains (5) summary
    cd00992
    Location:583 → 655
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08806
    Location:19 → 104
    CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
    cl17036
    Location:680 → 742
    SH3; Src Homology 3 domain superfamily
    cl17190
    Location:858 → 961
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    cl25732
    Location:151 → 448
    SMC_N; RecF/RecN/SMC N terminal domain

  4. NM_052819.3 → NP_438170.1  caspase recruitment domain-containing protein 14 isoform 2

    See identical proteins and their annotated locations for NP_438170.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) lacks several exons at the 5' and 3' ends and its transcription extends past a splice site that is used in variant 1. The encoded isoform 2 has a shorter N-terminus and a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC087741, BC001326
    UniProtKB/TrEMBL
    B4DKY0
    Related
    ENST00000573754.5
    Conserved Domains (2) summary
    COG1196
    Location:8 → 211
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    cd00992
    Location:346 → 381
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

RNA

  1. NR_047566.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) uses an alternate splice site in an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AC087741, AK091123, BU617627, DA461380
    Related
    ENST00000575500.5

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

    Range
    80170030..80209331
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047436713.1 → XP_047292669.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6
    Related
    ENSP00000499145.1, ENST00000651672.1

  2. XM_047436719.1 → XP_047292675.1  caspase recruitment domain-containing protein 14 isoform X3

  3. XM_047436714.1 → XP_047292670.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  4. XM_011525213.2 → XP_011523515.1  caspase recruitment domain-containing protein 14 isoform X1

    See identical proteins and their annotated locations for XP_011523515.1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6
    UniProtKB/TrEMBL
    A0A494C1N2
    Conserved Domains (5) summary
    cd00992
    Location:583 → 655
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08806
    Location:19 → 104
    CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
    cl17036
    Location:680 → 742
    SH3; Src Homology 3 domain superfamily
    cl17190
    Location:858 → 961
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    cl25732
    Location:151 → 448
    SMC_N; RecF/RecN/SMC N terminal domain

  5. XM_011525216.2 → XP_011523518.1  caspase recruitment domain-containing protein 14 isoform X1

    See identical proteins and their annotated locations for XP_011523518.1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6
    UniProtKB/TrEMBL
    A0A494C1N2
    Conserved Domains (5) summary
    cd00992
    Location:583 → 655
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08806
    Location:19 → 104
    CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
    cl17036
    Location:680 → 742
    SH3; Src Homology 3 domain superfamily
    cl17190
    Location:858 → 961
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    cl25732
    Location:151 → 448
    SMC_N; RecF/RecN/SMC N terminal domain

  6. XM_011525218.2 → XP_011523520.1  caspase recruitment domain-containing protein 14 isoform X1

    See identical proteins and their annotated locations for XP_011523520.1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6
    UniProtKB/TrEMBL
    A0A494C1N2
    Conserved Domains (5) summary
    cd00992
    Location:583 → 655
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd08806
    Location:19 → 104
    CARD_CARD14_CARMA2; Caspase activation and recruitment domain of CARD14-like proteins
    cl17036
    Location:680 → 742
    SH3; Src Homology 3 domain superfamily
    cl17190
    Location:858 → 961
    NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
    cl25732
    Location:151 → 448
    SMC_N; RecF/RecN/SMC N terminal domain

  7. XM_047436715.1 → XP_047292671.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6
    Related
    ENSP00000458715.1, ENST00000573882.5

  8. XM_047436717.1 → XP_047292673.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  9. XM_047436716.1 → XP_047292672.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  10. XM_047436718.1 → XP_047292674.1  caspase recruitment domain-containing protein 14 isoform X2

  11. XM_047436720.1 → XP_047292676.1  caspase recruitment domain-containing protein 14 isoform X4

    UniProtKB/TrEMBL
    A0A494C0J4
    Related
    ENSP00000498570.1, ENST00000650867.1

  12. XM_047436721.1 → XP_047292677.1  caspase recruitment domain-containing protein 14 isoform X5

  13. XM_047436722.1 → XP_047292678.1  caspase recruitment domain-containing protein 14 isoform X6

    UniProtKB/TrEMBL
    A0A994J6G4
    Related
    ENSP00000515382.1, ENST00000703566.1

  14. XM_047436723.1 → XP_047292679.1  caspase recruitment domain-containing protein 14 isoform X7

    Related
    ENSP00000498274.1, ENST00000651068.1

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791802.1 Reference GRCh38.p14 PATCHES

    Range
    194698..234037
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054333205.1 → XP_054189180.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  2. XM_054333202.1 → XP_054189177.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  3. XM_054333204.1 → XP_054189179.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  4. XM_054333200.1 → XP_054189175.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  5. XM_054333209.1 → XP_054189184.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  6. XM_054333208.1 → XP_054189183.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  7. XM_054333201.1 → XP_054189176.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  8. XM_054333206.1 → XP_054189181.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  9. XM_054333203.1 → XP_054189178.1  caspase recruitment domain-containing protein 14 isoform X1

    UniProtKB/Swiss-Prot
    B8QQJ3, Q9BVB5, Q9BXL6

  10. XM_054333207.1 → XP_054189182.1  caspase recruitment domain-containing protein 14 isoform X2

  11. XM_054333210.1 → XP_054189185.1  caspase recruitment domain-containing protein 14 isoform X4

    UniProtKB/TrEMBL
    A0A494C0J4

  12. XM_054333211.1 → XP_054189186.1  caspase recruitment domain-containing protein 14 isoform X5

  13. XM_054333212.1 → XP_054189187.1  caspase recruitment domain-containing protein 14 isoform X6

    UniProtKB/TrEMBL
    A0A994J6G4

  14. XM_054333213.1 → XP_054189188.1  caspase recruitment domain-containing protein 14 isoform X7

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060941.1 Alternate T2T-CHM13v2.0

    Range
    81070412..81109756
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054317155.1 → XP_054173130.1  caspase recruitment domain-containing protein 14 isoform X1

  2. XM_054317152.1 → XP_054173127.1  caspase recruitment domain-containing protein 14 isoform X1

  3. XM_054317154.1 → XP_054173129.1  caspase recruitment domain-containing protein 14 isoform X1

  4. XM_054317150.1 → XP_054173125.1  caspase recruitment domain-containing protein 14 isoform X1

  5. XM_054317159.1 → XP_054173134.1  caspase recruitment domain-containing protein 14 isoform X1

  6. XM_054317158.1 → XP_054173133.1  caspase recruitment domain-containing protein 14 isoform X1

  7. XM_054317151.1 → XP_054173126.1  caspase recruitment domain-containing protein 14 isoform X1

  8. XM_054317156.1 → XP_054173131.1  caspase recruitment domain-containing protein 14 isoform X1

  9. XM_054317153.1 → XP_054173128.1  caspase recruitment domain-containing protein 14 isoform X1

  10. XM_054317157.1 → XP_054173132.1  caspase recruitment domain-containing protein 14 isoform X2

  11. XM_054317160.1 → XP_054173135.1  caspase recruitment domain-containing protein 14 isoform X4

  12. XM_054317161.1 → XP_054173136.1  caspase recruitment domain-containing protein 14 isoform X5

  13. XM_054317162.1 → XP_054173137.1  caspase recruitment domain-containing protein 14 isoform X6

  14. XM_054317163.1 → XP_054173138.1  caspase recruitment domain-containing protein 14 isoform X7

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9BXL6.2 GenPept UniProtKB/Swiss-Prot:Q9BXL6

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