ddx28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ddx28provided by ZNC
Official Full Name: DEAD (Asp-Glu-Ala-Asp) box polypeptide 28provided by ZNC
Primary source: ZFIN:ZDB-GENE-061013-64
See related: Ensembl:ENSDARG00000060411 AllianceGenome:ZFIN:ZDB-GENE-061013-64
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:153386
Summary: Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and nucleic acid binding activity. Predicted to be involved in mitochondrial large ribosomal subunit assembly. Predicted to be active in mitochondrion. Orthologous to human DDX28 (DEAD-box helicase 28). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 7

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (34963755..34965654)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (34692278..34694177)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables RNA helicase activity	IEA Inferred from Electronic Annotation more info
enables helicase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in mitochondrial large ribosomal subunit assembly	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: probable ATP-dependent RNA helicase DDX28

NP_001070800.1

EC 3.6.4.13

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001077332.1 → NP_001070800.1 probable ATP-dependent RNA helicase DDX28

See identical proteins and their annotated locations for NP_001070800.1

Status: PROVISIONAL

Source sequence(s)

BC124668

UniProtKB/TrEMBL

Q08BL1

Related

ENSDARP00000079522.3, ENSDART00000085087.6

Conserved Domains (3) summary

COG0513
Location:137 → 556

SrmB; Superfamily II DNA and RNA helicase [Replication, recombination and repair]

pfam00271
Location:395 → 506

Helicase_C; Helicase conserved C-terminal domain

cl21455
Location:153 → 362

P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases