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abi3a ABI family, member 3a [ Danio rerio (zebrafish) ]

Gene ID: 767807, updated on 9-Dec-2024

Summary

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Official Symbol
abi3aprovided by ZNC
Official Full Name
ABI family, member 3aprovided by ZNC
Primary source
ZFIN:ZDB-GENE-060929-958
See related
Ensembl:ENSDARG00000060072 AllianceGenome:ZFIN:ZDB-GENE-060929-958
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
zgc:153739
Summary
Predicted to enable SH3 domain binding activity and signaling adaptor activity. Predicted to be involved in neuron migration. Predicted to be located in filopodium. Predicted to be part of SCAR complex. Predicted to be active in actin-based cell projection and lamellipodium. Orthologous to human ABI3 (ABI family member 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
all
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Genomic context

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See abi3a in Genome Data Viewer
Location:
chromosome: 3
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (33395942..33417826, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (33264228..33286255, complement)

Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene MAGUK p55 scaffold protein 2a Neighboring gene si:dkey-283b1.6 Neighboring gene dynein axonemal assembly factor 19 Neighboring gene ribosomal protein L23

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Zebrafish Collagen Type I: Molecular and Biochemical Characterization of the Major Structural Protein in Bone and Skin. Gistelinck C, et al. Sci Rep, 2016 Feb 15. PMID 26876635, Free PMC Article
  2. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
  3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
  4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC153739

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in filopodium IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
ABI family, member 3a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001076774.2 → NP_001070242.2  ABI family, member 3a

    Status: VALIDATED

    Source sequence(s)
    CR396582
    UniProtKB/TrEMBL
    Q08C24
    Related
    ENSDARP00000078719.5, ENSDART00000084284.7
    Conserved Domains (2) summary
    cd11826
    Location:400 → 451
    SH3_Abi; Src homology 3 domain of Abl Interactor proteins
    pfam07815
    Location:99 → 177
    Abi_HHR; Abl-interactor HHR

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007114.7 Reference GRCz11 Primary Assembly

    Range
    33395942..33417826 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005164048.5 → XP_005164105.1  ABI family, member 3a isoform X1

    UniProtKB/TrEMBL
    A0A8M2BBC3, Q08C24
    Conserved Domains (2) summary
    cd11826
    Location:476 → 527
    SH3_Abi; Src homology 3 domain of Abl Interactor proteins
    pfam07815
    Location:99 → 177
    Abi_HHR; Abl-interactor HHR

  2. XM_021471554.2 → XP_021327229.1  ABI family, member 3a isoform X2

    UniProtKB/TrEMBL
    A0A8M9PQS9
    Conserved Domains (1) summary
    pfam07815
    Location:99 → 177
    Abi_HHR; Abl-interactor HHR
Nucleotide Protein Strain
Heading Accession and Version

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