U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

dfrA27 trimethoprim-resistant dihydrofolate reductase DfrA27 [ Shewanella xiamenensis ]

Gene ID: 75186320, updated on 3-Dec-2024

Summary

Gene symbol
dfrA27
Gene description
trimethoprim-resistant dihydrofolate reductase DfrA27
Locus tag
KXJ80_RS00760
Gene type
protein coding
Organism
Shewanella xiamenensis (strain: HD6416)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales; Shewanellaceae; Shewanella
Old locus tag
KXJ80_00760
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Location:
plasmid: pHD6416-NDM

NZ_CP079717.1Genomic Context describing neighboring genes Neighboring gene class 1 integron integrase IntI1 Neighboring gene NAD(+)--rifampin ADP-ribosyltransferase Arr-3 Neighboring gene ANT(3'')-Ia family aminoglycoside nucleotidyltransferase AadA16 Neighboring gene quaternary ammonium compound efflux SMR transporter QacE delta 1 Neighboring gene sulfonamide-resistant dihydropteroate synthase Sul1

General protein information

Preferred Names
trimethoprim-resistant dihydrofolate reductase DfrA27

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP079717.1 Reference assembly

    Range
    150685..151158
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_001749985.1 MULTISPECIES: trimethoprim-resistant dihydrofolate reductase DfrA27 [Bacteria]

    See identical proteins and their annotated locations for WP_001749985.1

    UniProtKB/TrEMBL
    A0A089GI04, A0A0N9E4A4, A0A0S1LIP8, A0A0S1VX02, A0A1L3HNW3, A0A1V0M3L5, A0A248LLU8, A0A373F474, A0A387K1D9, A0A3G8EXC9, A0A3Q8DJL2, A0A427UM35, A0A4Q2QTN5, A0A501W6Q2, A0A610H697, A0A6L8MC80, A0A6M4NNZ8, A0A7G5F4J2, A0A7T7GQP6, A0A9X4GI75, A0AA42FG44, A0AA44RED0, A0AA96M7Z1, A0AA97GQ46, A0AAJ5IM52, A0AAN0L838, A0AAP6DB85, A0AAP9AF58, A0AAW9AXR1, A0AAW9BMY9, B2ZNP4, B2ZPD3, B9V4W1, E5D593, F8S0D8, I1W6I2, R4V067, R9URM3, T1RTL1
    Conserved Domains (1) summary
    cd00209
    Location:3155
    DHFR; Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5, ...