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tolC outer membrane channel protein TolC [ Shigella dysenteriae ]

Gene ID: 75173161, updated on 3-Dec-2024

Summary

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Gene symbol
tolC
Gene description
outer membrane channel protein TolC
Locus tag
HUZ68_RS19205
Gene type
protein coding
Organism
Shigella dysenteriae (strain: SWHEFF_49)
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Shigella
Old locus tag
HUZ68_19040
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Genomic context

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NZ_CP055055.1Genomic Context describing neighboring genes Neighboring gene DUF1249 family protein Neighboring gene ADP-ribose diphosphatase Neighboring gene DUF1190 family protein Neighboring gene glutathionylspermidine synthase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP055055.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export. Koronakis V, et al. Nature, 2000 Jun 22. PMID 10879525
  2. Structure of TolC, the outer membrane component of the bacterial type I efflux system, derived from two-dimensional crystals. Koronakis V, et al. Mol Microbiol, 1997 Feb. PMID 9044294
  3. Expression of the AcrAB Components of the AcrAB-TolC Multidrug Efflux Pump of Yersinia enterocolitica Is Subject to Dual Regulation by OmpR. Raczkowska A, et al. PLoS One, 2015. PMID 25893523, Free PMC Article
  4. High-resolution genomic surveillance elucidates a multilayered hierarchical transfer of resistance between WWTP- and human/animal-associated bacteria. Che Y, et al. Microbiome, 2022 Jan 25. PMID 35078531, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
outer membrane channel protein TolC

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP055055.1 Reference assembly

    Range
    4028188..4029669
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    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_000735278.1 MULTISPECIES: outer membrane channel protein TolC [Enterobacteriaceae]

    See identical proteins and their annotated locations for WP_000735278.1

    UniProtKB/Swiss-Prot
    P02930, Q2M9G5
    UniProtKB/TrEMBL
    A0A0E0XU07, A0A0H3MKL8, A0A0H9L714, A0A140N6A8, A0A1S9JNV8, A0A2A2XFF7, A0A379ZTS3, A0A6H2GML3, A0A7U9NYL9, A0A836NA81, A0A8E0KUM2, A0A9P2IDQ1, A0AA35F7V2, A0AAD2VEN3, A0AAD2ZCF8, A0AAN1S8B5, A0AAN4AYG5, A0AAN4NR90, B7LGH5, E0IVX0, F5NZF4, W8T9H1
    Conserved Domains (1) summary
    PRK09465
    Location:1 → 451
    tolC; outer membrane channel protein; Reviewed
Nucleotide Protein
Heading Accession and Version