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ptgdsb.2 prostaglandin D2 synthase b, tandem duplicate 2 [ Danio rerio (zebrafish) ]

Gene ID: 751701, updated on 4-Jan-2025

Summary

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Official Symbol
ptgdsb.2provided by ZNC
Official Full Name
prostaglandin D2 synthase b, tandem duplicate 2provided by ZNC
Primary source
ZFIN:ZDB-GENE-030911-3
See related
Ensembl:ENSDARG00000071626 AllianceGenome:ZFIN:ZDB-GENE-030911-3
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Danio rerio
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as
cb193; ptgdsl; id:ibd5130; id:ibd5159; wu:fb15e12; zgc:153154; zgc:158768
Summary
Predicted to enable small molecule binding activity. Predicted to be located in extracellular region. Is expressed in midbrain neural keel; neural plate; neural tube; segmental plate; and somite. Human ortholog(s) of this gene implicated in carotid artery disease. Orthologous to several human genes including PTGDS (prostaglandin D2 synthase). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

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See ptgdsb.2 in Genome Data Viewer
Location:
chromosome: 24
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (17021513..17023392, complement)
105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (16877094..16878973, complement)

Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 2, subunit 3 gamma Neighboring gene zinc finger protein X-linked Neighboring gene prostaglandin D2 synthase b, tandem duplicate 1 Neighboring gene complement component 8, gamma polypeptide

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
  • BioProject: PRJEB1986
  • Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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Related articles in PubMed

  1. Interleukin-11 signaling promotes cellular reprogramming and limits fibrotic scarring during tissue regeneration. Allanki S, et al. Sci Adv, 2021 Sep 10. PMID 34516874, Free PMC Article
  2. Genome-wide analysis of facial skeletal regionalization in zebrafish. Askary A, et al. Development, 2017 Aug 15. PMID 28705894, Free PMC Article
  3. Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo. Wagner DE, et al. Science, 2018 Jun 1. PMID 29700229, Free PMC Article
  4. Understanding the complexity of epimorphic regeneration in zebrafish caudal fin tissue: A transcriptomic and proteomic approach. Banu S, et al. Genomics, 2022 Mar. PMID 35134499
  5. A gene expression screen in zebrafish embryogenesis. Kudoh T, et al. Genome Res, 2001 Dec. PMID 11731487

See all (9) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Clone Names

  • MGC153154, MGC158768

Gene Ontology Provided by ZFIN

Function Evidence Code Pubs
enables small molecule binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
prostaglandin D2 synthase b, tandem duplicate 2
Names
prostaglandin D2 synthase like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001045413.1 → NP_001038878.1  prostaglandin D2 synthase b, tandem duplicate 2 precursor

    See identical proteins and their annotated locations for NP_001038878.1

    Status: PROVISIONAL

    Source sequence(s)
    BC122162
    UniProtKB/TrEMBL
    Q0P4C2
    Related
    ENSDARP00000096836.3, ENSDART00000106058.5
    Conserved Domains (1) summary
    pfam00061
    Location:35 → 175
    Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

  1. NC_007135.7 Reference GRCz11 Primary Assembly

    Range
    17021513..17023392 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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