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walK cell wall metabolism sensor histidine kinase WalK [ Lysinibacillus capsici ]

Gene ID: 74903065, updated on 23-Nov-2024

Summary

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Gene symbol
walK
Gene description
cell wall metabolism sensor histidine kinase WalK
Locus tag
LCP48_RS00165
Gene type
protein coding
Organism
Lysinibacillus capsici (strain: anQ-h6)
Lineage
Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Lysinibacillus
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Genomic context

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NZ_CP084108.1Genomic Context describing neighboring genes Neighboring gene MBL fold metallo-hydrolase Neighboring gene two-component system regulatory protein YycI Neighboring gene YycH family regulatory protein Neighboring gene response regulator YycF Neighboring gene peptidoglycan DD-metalloendopeptidase family protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP084108.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A vancomycin resistance-associated WalK(S221P) mutation attenuates the virulence of vancomycin-intermediate Staphylococcus aureus. Rao Y, et al. J Adv Res, 2022 Sep. PMID 36100324, Free PMC Article
  2. Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus. Monk IR, et al. Nat Commun, 2019 Jul 11. PMID 31296851, Free PMC Article
  3. New insights into the WalK/WalR (YycG/YycF) essential signal transduction pathway reveal a major role in controlling cell wall metabolism and biofilm formation in Staphylococcus aureus. Dubrac S, et al. J Bacteriol, 2007 Nov. PMID 17827301, Free PMC Article

GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
cell wall metabolism sensor histidine kinase WalK
WP_004233382.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP084108.1 Reference assembly

    Range
    29008..30873 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_004233382.1 MULTISPECIES: cell wall metabolism sensor histidine kinase WalK [Lysinibacillus]

    See identical proteins and their annotated locations for WP_004233382.1

    Conserved Domains (5) summary
    smart00091
    Location:274 → 335
    PAS; PAS domain
    smart00387
    Location:499 → 609
    HATPase_c; Histidine kinase-like ATPases
    smart00388
    Location:388 → 453
    HisKA; His Kinase A (phosphoacceptor) domain
    COG5002
    Location:168 → 621
    VicK; Signal transduction histidine kinase [Signal transduction mechanisms]
    pfam00672
    Location:195 → 264
    HAMP; HAMP domain