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Fam110d family with sequence similarity 110, member D [ Mus musculus (house mouse) ]

Gene ID: 72690, updated on 4-Jan-2025

Summary

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Official Symbol
Fam110dprovided by MGI
Official Full Name
family with sequence similarity 110, member Dprovided by MGI
Primary source
MGI:MGI:1919940
See related
Ensembl:ENSMUSG00000050105 AllianceGenome:MGI:1919940
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Grrp1; 2810043G13Rik
Summary
Is expressed in several structures, including alimentary system; brain ventricular layer; cranium; limb; and sensory organ epithelium. Orthologous to human FAM110D (family with sequence similarity 110 member D). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Broad expression in ovary adult (RPKM 9.1), lung adult (RPKM 8.2) and 24 other tissues See more
Orthologs
human all
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Genomic context

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See Fam110d in Genome Data Viewer
Location:
4 D2.3; 4 66.5 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (133978413..133993528, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (134251102..134266196, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7997 Neighboring gene Zfp593 opposite strand Neighboring gene zinc finger protein 593 Neighboring gene predicted gene, 30191 Neighboring gene predicted gene, 42325 Neighboring gene STARR-positive B cell enhancer ABC_E4679 Neighboring gene PDLIM1 interacting kinase 1 like Neighboring gene tripartite motif-containing 63 Neighboring gene STARR-seq mESC enhancer starr_11671

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Id genes are essential for early heart formation. Cunningham TJ, et al. Genes Dev, 2017 Jul 1. PMID 28794185, Free PMC Article
  2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
  3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  5. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
  
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
  

General protein information

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Preferred Names
protein FAM110D
Names
glycine/arginine rich protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099296.2 → NP_001092766.1  protein FAM110D

    See identical proteins and their annotated locations for NP_001092766.1

    Status: VALIDATED

    Source sequence(s)
    BB578755, BC048704
    Consensus CDS
    CCDS38913.1
    UniProtKB/Swiss-Prot
    Q80X91
    Related
    ENSMUSP00000060143.6, ENSMUST00000060050.6
    Conserved Domains (2) summary
    pfam14160
    Location:141 → 262
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:13 → 41
    FAM110_N; Centrosome-associated N-terminus

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    133978413..133993528 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036164465.1 → XP_036020358.1  protein FAM110D isoform X2

    UniProtKB/Swiss-Prot
    Q80X91
    Conserved Domains (2) summary
    pfam14160
    Location:141 → 262
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:13 → 41
    FAM110_N; Centrosome-associated N-terminus

  2. XM_006539198.4 → XP_006539261.1  protein FAM110D isoform X2

    See identical proteins and their annotated locations for XP_006539261.1

    UniProtKB/Swiss-Prot
    Q80X91
    Conserved Domains (2) summary
    pfam14160
    Location:141 → 262
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:13 → 41
    FAM110_N; Centrosome-associated N-terminus

  3. XM_006539199.3 → XP_006539262.1  protein FAM110D isoform X2

    See identical proteins and their annotated locations for XP_006539262.1

    UniProtKB/Swiss-Prot
    Q80X91
    Conserved Domains (2) summary
    pfam14160
    Location:141 → 262
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:13 → 41
    FAM110_N; Centrosome-associated N-terminus

  4. XM_036164464.1 → XP_036020357.1  protein FAM110D isoform X2

    UniProtKB/Swiss-Prot
    Q80X91
    Conserved Domains (2) summary
    pfam14160
    Location:141 → 262
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:13 → 41
    FAM110_N; Centrosome-associated N-terminus

  5. XM_006539200.3 → XP_006539263.1  protein FAM110D isoform X2

    See identical proteins and their annotated locations for XP_006539263.1

    UniProtKB/Swiss-Prot
    Q80X91
    Conserved Domains (2) summary
    pfam14160
    Location:141 → 262
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:13 → 41
    FAM110_N; Centrosome-associated N-terminus

  6. XM_006539197.4 → XP_006539260.1  protein FAM110D isoform X1

    Conserved Domains (2) summary
    pfam14160
    Location:173 → 294
    FAM110_C; Centrosome-associated C-terminus
    pfam14161
    Location:45 → 73
    FAM110_N; Centrosome-associated N-terminus
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q80X91.2 GenPept UniProtKB/Swiss-Prot:Q80X91

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