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dfrA14 trimethoprim-resistant dihydrofolate reductase DfrA14 [ Edwardsiella piscicida ]

Gene ID: 72530332, updated on 3-Dec-2024

Summary

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Gene symbol
dfrA14
Gene description
trimethoprim-resistant dihydrofolate reductase DfrA14
Locus tag
L1P05_RS17180
Gene type
protein coding
Organism
Edwardsiella piscicida (strain: 18EpOKYJ, nat-host: Paralichthtys olivaceus (Olive flounder))
Lineage
Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Hafniaceae; Edwardsiella
Old locus tag
L1P05_17180
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Genomic context

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Location:
plasmid: unnamed

NZ_CP090969.1Genomic Context describing neighboring genes Neighboring gene recombinase family protein Neighboring gene class 1 integron integrase IntI1 Neighboring gene pseudo Neighboring gene pseudo

Genomic regions, transcripts, and products

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Genomic Sequence:
NZ_CP090969.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General protein information

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Preferred Names
trimethoprim-resistant dihydrofolate reductase DfrA14

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NZ_CP090969.1 Reference assembly

    Range
    3842..4315
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. WP_004201280.1 MULTISPECIES: trimethoprim-resistant dihydrofolate reductase DfrA14 [Pseudomonadota]

    See identical proteins and their annotated locations for WP_004201280.1

    UniProtKB/TrEMBL
    A0A0E1CMR8, A0A126JT23, A0A1P8VM94, A0A1P8VMF0, A0A1Z1VVZ2, A0A221KLI8, A0A250ME49, A0A2H4UE77, A0A2H5CP70, A0A2K9V0D2, A0A3U9YMQ8, A0A411AMV1, A0A499RKL6, A0A4D6FW28, A0A4Q8P8E7, A0A4U8ICA3, A0A5B0K321, A0A5J0PE70, A0A5J6X2I6, A0A5Q8BUM6, A0A5V8LHU1, A0A5V9GQ34, A0A5W3F2W5, A0A5W6EWD8, A0A5X0GA87, A0A5X0KL66, A0A5X4GDB5, A0A6M4NKT3, A0A7U9NXU4, A0A7V7JAC8, A0A899NFS0, A0A8H9P1D4, A0A8I0G974, A0A8I1KHJ4, A0A9P3TNY6, A0A9W3LFW4, A0AAD2YT40, A0AAE4E2B0, A0AAE4J725, A0AAI8IQV4, A0AAI9GPU1, A0AAJ5S8W2, A0AAP2K1Z9, A0AAQ3H6I0, A0AAW8HKB3, A0AAW8ZGR2, A7Y2S5, D7PM81, D7RU25, F8T8W2, Q2Q3Z8, Q573P5
    Conserved Domains (1) summary
    cd00209
    Location:3 → 155
    DHFR; Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5, ...