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ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 722449, updated on 17-Aug-2024

Summary

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Official Symbol
ABL1provided by VGNC
Official Full Name
ABL proto-oncogene 1, non-receptor tyrosine kinaseprovided by VGNC
Primary source
VGNC:VGNC:69585
See related
Ensembl:ENSMMUG00000012499
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See ABL1 in Genome Data Viewer
Location:
chromosome: 15
Exon count:
12
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (9599097..9784123, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (7776370..7960828, complement)

Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene fibrinogen C domain containing 1 Neighboring gene pyroglutamylated RFamide peptide Neighboring gene 60S ribosomal protein L37 pseudogene Neighboring gene exosome component 2 Neighboring gene PR/SET domain 12

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase ABL1
Names
c-abl oncogene 1, non-receptor tyrosine kinase
c-abl oncogene 1, receptor tyrosine kinase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041768.1 Reference Mmul_10 Primary Assembly

    Range
    9599097..9784123 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015116552.2 → XP_014972038.2  tyrosine-protein kinase ABL1 isoform X2

    UniProtKB/TrEMBL
    F7EH78, I0FQI2
    Related
    ENSMMUP00000016419.4, ENSMMUT00000017534.4
    Conserved Domains (4) summary
    smart00808
    Location:1006 → 1130
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:123 → 216
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:65 → 118
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:235 → 497
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase

  2. XM_015116551.2 → XP_014972037.2  tyrosine-protein kinase ABL1 isoform X1

    UniProtKB/TrEMBL
    A0A1D5R032, G7NFJ0, H9YUX8
    Related
    ENSMMUP00000053665.2, ENSMMUT00000068222.2
    Conserved Domains (4) summary
    smart00808
    Location:1025 → 1149
    FABD; F-actin binding domain (FABD)
    cd09935
    Location:142 → 235
    SH2_ABL; Src homology 2 (SH2) domain found in Abelson murine lymphosarcoma virus (ABL) proteins
    cd11850
    Location:84 → 137
    SH3_Abl; Src homology 3 domain of the Protein Tyrosine Kinase, Abelson kinase
    cd05052
    Location:254 → 516
    PTKc_Abl; Catalytic domain of the Protein Tyrosine Kinase, Abelson kinase
Nucleotide Protein
Heading Accession and Version

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