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FXR2 FMR1 autosomal homolog 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 721889, updated on 17-Aug-2024

Summary

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Official Symbol
FXR2provided by VGNC
Official Full Name
FMR1 autosomal homolog 2provided by VGNC
Primary source
VGNC:VGNC:99153
See related
Ensembl:ENSMMUG00000013510
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See FXR2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
17
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (7367407..7393000, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (7570926..7596872, complement)

Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene MPDU1 antisense RNA 1 Neighboring gene mannose-P-dolichol utilization defect 1 Neighboring gene uncharacterized LOC114673048 Neighboring gene SRY-box transcription factor 15 Neighboring gene small nucleolar RNA U13 Neighboring gene spermidine/spermine N1-acetyltransferase family member 2 Neighboring gene sex hormone binding globulin

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anterograde axonal transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of alternative mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendrite morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendritic spine development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of filopodium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mRNA stability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of modification of synaptic structure IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of translation at postsynapse, modulating synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic filopodium IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine neck IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal ribonucleoprotein granule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
RNA-binding protein FXR2; fragile X mental retardation syndrome-related protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266676.1 → NP_001253605.1  RNA-binding protein FXR2

    See identical proteins and their annotated locations for NP_001253605.1

    Status: PROVISIONAL

    Source sequence(s)
    JV043864
    UniProtKB/TrEMBL
    G7NIG5, I0FHK9
    Related
    ENSMMUP00000064048.1, ENSMMUT00000107473.1
    Conserved Domains (5) summary
    pfam12235
    Location:364 → 473
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:510 → 577
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    cd20473
    Location:13 → 67
    Tudor_Agenet_FXR2_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 2 (FXR2) and similar proteins
    cd20476
    Location:69 → 136
    Tudor_Agenet_FXR2_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 2 (FXR2) and similar proteins
    cl00098
    Location:291 → 368
    KH-I; K homology (KH) RNA-binding domain, type I

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041769.1 Reference Mmul_10 Primary Assembly

    Range
    7367407..7393000 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028835784.1 → XP_028691617.1  fragile X mental retardation syndrome-related protein 2 isoform X1

    UniProtKB/TrEMBL
    G7NIG5
    Related
    ENSMMUP00000077968.1, ENSMMUT00000082458.1
    Conserved Domains (5) summary
    smart00322
    Location:187 → 247
    KH; K homology RNA-binding domain
    pfam12235
    Location:321 → 430
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:467 → 534
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam00013
    Location:252 → 319
    KH_1; KH domain
    pfam05641
    Location:29 → 84
    Agenet; Agenet domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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