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Zfp1006 zinc finger protein 1006 [ Mus musculus (house mouse) ]

Gene ID: 72139, updated on 27-Nov-2024

Summary

Official Symbol
Zfp1006provided by MGI
Official Full Name
zinc finger protein 1006provided by MGI
Primary source
MGI:MGI:1919389
See related
Ensembl:ENSMUSG00000071302 AllianceGenome:MGI:1919389
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610044O15Rik; 2610044O15Rik8
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be active in nucleoplasm. Orthologous to several human genes including ZNF117 (zinc finger protein 117); ZNF490 (zinc finger protein 490); and ZNF708 (zinc finger protein 708). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in bladder adult (RPKM 2.6), CNS E11.5 (RPKM 1.9) and 21 other tissues See more
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Genomic context

See Zfp1006 in Genome Data Viewer
Location:
8 E2; 8
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (129942835..129960527, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (129216354..129234046, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 7A Neighboring gene predicted gene, 22545 Neighboring gene STARR-seq mESC enhancer starr_23110 Neighboring gene coiled-coil domain containing 7B Neighboring gene STARR-seq mESC enhancer starr_23111 Neighboring gene STARR-seq mESC enhancer starr_23112 Neighboring gene STARR-seq mESC enhancer starr_23113 Neighboring gene predicted gene, 22374 Neighboring gene STARR-seq mESC enhancer starr_23114 Neighboring gene STARR-seq mESC enhancer starr_23115 Neighboring gene peroxiredoxin pseudogene 2 Neighboring gene predicted gene, 32856

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of cytokine production IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of immune system process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
uncharacterized protein LOC72139

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153780.3NP_722475.1  uncharacterized protein LOC72139

    See identical proteins and their annotated locations for NP_722475.1

    Status: VALIDATED

    Source sequence(s)
    AK138138
    Consensus CDS
    CCDS80947.1
    UniProtKB/TrEMBL
    E9Q1C8, Q8BG62
    Related
    ENSMUSP00000140736.2, ENSMUST00000190157.7
    Conserved Domains (1) summary
    pfam01352
    Location:441
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    129942835..129960527 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)