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SMG6 SMG6 nonsense mediated mRNA decay factor [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 721291, updated on 17-Aug-2024

Summary

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Official Symbol
SMG6provided by VGNC
Official Full Name
SMG6 nonsense mediated mRNA decay factorprovided by VGNC
Primary source
VGNC:VGNC:99262
See related
Ensembl:ENSMMUG00000023161
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See SMG6 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
22
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (1925069..2168768, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (1953141..2241045, complement)

Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene microRNA mir-212 Neighboring gene HIC ZBTB transcriptional repressor 1 Neighboring gene mitochondrial calcium uniporter regulator 1 pseudogene Neighboring gene small nucleolar RNA SNORD91 family Neighboring gene small nucleolar RNA SNORD91 family Neighboring gene serine racemase Neighboring gene TSR1 ribosome maturation factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomerase RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of telomerase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
telomerase-binding protein EST1A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041769.1 Reference Mmul_10 Primary Assembly

    Range
    1925069..2168768 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015118204.2 → XP_014973690.1  telomerase-binding protein EST1A isoform X1

    UniProtKB/TrEMBL
    F7FDL6, H9FRX6, I0FK17
    Related
    ENSMMUP00000030488.3, ENSMMUT00000032581.4
    Conserved Domains (4) summary
    cd09885
    Location:1241 → 1416
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    pfam05750
    Location:336 → 538
    Rubella_Capsid; Rubella capsid protein
    pfam10373
    Location:751 → 1103
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:638 → 741
    EST1; Telomerase activating protein Est1

  2. XM_015118207.2 → XP_014973693.1  telomerase-binding protein EST1A isoform X3

    UniProtKB/TrEMBL
    A0A5F7ZFU5, H9FRX6
    Related
    ENSMMUP00000064493.1, ENSMMUT00000106584.1
    Conserved Domains (4) summary
    cd09885
    Location:1210 → 1385
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    pfam05750
    Location:305 → 507
    Rubella_Capsid; Rubella capsid protein
    pfam10373
    Location:720 → 1072
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:607 → 710
    EST1; Telomerase activating protein Est1

  3. XM_015118206.2 → XP_014973692.1  telomerase-binding protein EST1A isoform X3

    UniProtKB/TrEMBL
    A0A5F7ZFU5, H9FRX6
    Related
    ENSMMUP00000068365.1, ENSMMUT00000105272.1
    Conserved Domains (4) summary
    cd09885
    Location:1210 → 1385
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    pfam05750
    Location:305 → 507
    Rubella_Capsid; Rubella capsid protein
    pfam10373
    Location:720 → 1072
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:607 → 710
    EST1; Telomerase activating protein Est1

  4. XM_015118205.2 → XP_014973691.1  telomerase-binding protein EST1A isoform X2

    UniProtKB/TrEMBL
    H9FRX6
    Conserved Domains (4) summary
    cd09885
    Location:1230 → 1405
    PIN_Smg6; PIN domain of human telomerase-binding protein EST1, Smg6, and other similar eukaryotic homologs
    pfam05750
    Location:325 → 527
    Rubella_Capsid; Rubella capsid protein
    pfam10373
    Location:740 → 1092
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:627 → 730
    EST1; Telomerase activating protein Est1
Nucleotide Protein
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