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LOC721002 immunoglobulin heavy variable 4-39 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 721002, updated on 9-Nov-2023

Summary

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Gene symbol
LOC721002
Gene description
immunoglobulin heavy variable 4-39
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
IGH; IGHV; IGHV4; IGHV4-F
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Genomic context

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See LOC721002 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
3
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 7 NC_041760.1 (169048790..169049750, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 7 NC_027899.1 (169314950..169315781)

Chromosome 7 - NC_041760.1Genomic Context describing neighboring genes Neighboring gene immunoglobulin heavy variable 7-4-1-like Neighboring gene immunoglobulin heavy variable 2-5-like Neighboring gene immunoglobulin heavy variable 3-23 Neighboring gene immunoglobulin heavy variable 3-23-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Roark RS, et al. Science, 2021 Jan 8. PMID 33214287, Free PMC Article
  2. Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization. Francica JR, et al. Nat Commun, 2015 Apr 10. PMID 25858157, Free PMC Article
  3. Single-cell and deep sequencing of IgG-switched macaque B cells reveal a diverse Ig repertoire following immunization. Sundling C, et al. J Immunol, 2014 Apr 15. PMID 24623130, Free PMC Article
  4. Rhesus and cynomolgus macaque immunoglobulin heavy-chain genotyping yields comprehensive databases of germline VDJ alleles. Vázquez Bernat N, et al. Immunity, 2021 Feb 9. PMID 33484642
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables antigen binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables immunoglobulin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in complement activation, classical pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phagocytosis, engulfment IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phagocytosis, recognition IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of B cell activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of immunoglobulin complex, circulating IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: immunoglobulin heavy variable 4-39
Names
immunoglobulin heavy chain VDJ region
immunoglobulin heavy chain variable region

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041760.1 Reference Mmul_10 Primary Assembly

    Range
    169048790..169049750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015144643.2 → XP_015000129.2  LOW QUALITY PROTEIN: immunoglobulin heavy variable 4-39

    Conserved Domains (1) summary
    cl11960
    Location:132 → 221
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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