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HIRA histone cell cycle regulator [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 719142, updated on 17-Aug-2024

Summary

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Official Symbol
HIRAprovided by VGNC
Official Full Name
histone cell cycle regulatorprovided by VGNC
Primary source
VGNC:VGNC:96714
See related
Ensembl:ENSMMUG00000009650
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See HIRA in Genome Data Viewer
Location:
chromosome: 10
Exon count:
28
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (33220499..33322860)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 10 NC_027902.1 (61031568..61137232, complement)

Chromosome 10 - NC_041763.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114670393 Neighboring gene chromosome 10 C22orf39 homolog Neighboring gene mitochondrial ribosomal protein L40 Neighboring gene clathrin heavy chain like 1 Neighboring gene small nucleolar RNA SNORA15 Neighboring gene solute carrier family 25 member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables nucleosome binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of HIR complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein HIRA
Names
HIR histone cell cycle regulation defective homolog A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257749.1 → NP_001244678.1  protein HIRA

    See identical proteins and their annotated locations for NP_001244678.1

    Status: PROVISIONAL

    Source sequence(s)
    JU336203
    UniProtKB/TrEMBL
    F6YJT8, H9ZD31
    Related
    ENSMMUP00000063538.1, ENSMMUT00000084072.1
    Conserved Domains (6) summary
    COG2319
    Location:7 → 372
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:7 → 352
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    pfam07569
    Location:764 → 955
    Hira; TUP1-like enhancer of split
    pfam09453
    Location:449 → 470
    HIRA_B; HIRA B motif
    pfam12341
    Location:728 → 796
    Mcl1_mid; Minichromosome loss protein, Mcl1, middle region
    sd00039
    Location:16 → 61
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041763.1 Reference Mmul_10 Primary Assembly

    Range
    33220499..33322860
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015149645.2 → XP_015005131.1  protein HIRA isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZHE5, A0A5F7ZIA9
    Related
    ENSMMUP00000065011.1, ENSMMUT00000092741.1
    Conserved Domains (5) summary
    COG2319
    Location:7 → 372
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:7 → 352
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    pfam07569
    Location:764 → 949
    Hira; TUP1-like enhancer of split
    pfam09453
    Location:449 → 470
    HIRA_B; HIRA B motif
    sd00039
    Location:16 → 61
    7WD40; WD40 repeat [structural motif]

  2. XM_028827445.1 → XP_028683278.1  protein HIRA isoform X3

    UniProtKB/TrEMBL
    A0A5F8A9B1
    Conserved Domains (5) summary
    sd00039
    Location:2 → 38
    7WD40; WD40 repeat [structural motif]
    pfam09453
    Location:315 → 336
    HIRA_B; HIRA B motif
    pfam03546
    Location:365 → 585
    Treacle; Treacher Collins syndrome protein Treacle
    pfam07569
    Location:631 → 815
    Hira; TUP1-like enhancer of split
    cl29593
    Location:1 → 218
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  3. XM_015149650.2 → XP_015005136.1  protein HIRA isoform X3

    UniProtKB/TrEMBL
    A0A5F8A9B1
    Conserved Domains (5) summary
    sd00039
    Location:2 → 38
    7WD40; WD40 repeat [structural motif]
    pfam09453
    Location:315 → 336
    HIRA_B; HIRA B motif
    pfam03546
    Location:365 → 585
    Treacle; Treacher Collins syndrome protein Treacle
    pfam07569
    Location:631 → 815
    Hira; TUP1-like enhancer of split
    cl29593
    Location:1 → 218
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  4. XM_015149647.2 → XP_015005133.1  protein HIRA isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZMT9
    Related
    ENSMMUP00000065931.1, ENSMMUT00000103751.1
    Conserved Domains (6) summary
    COG2319
    Location:1 → 279
    WD40; WD40 repeat [General function prediction only]
    pfam07569
    Location:682 → 867
    Hira; TUP1-like enhancer of split
    pfam09453
    Location:367 → 388
    HIRA_B; HIRA B motif
    pfam12341
    Location:646 → 714
    Mcl1_mid; Minichromosome loss protein, Mcl1, middle region
    sd00039
    Location:53 → 90
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:2 → 270
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  5. XM_015149648.2 → XP_015005134.1  protein HIRA isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZMT9
    Related
    ENSMMUP00000073098.1, ENSMMUT00000090174.1
    Conserved Domains (6) summary
    COG2319
    Location:1 → 279
    WD40; WD40 repeat [General function prediction only]
    pfam07569
    Location:682 → 867
    Hira; TUP1-like enhancer of split
    pfam09453
    Location:367 → 388
    HIRA_B; HIRA B motif
    pfam12341
    Location:646 → 714
    Mcl1_mid; Minichromosome loss protein, Mcl1, middle region
    sd00039
    Location:53 → 90
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:2 → 270
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  6. XM_015149649.2 → XP_015005135.1  protein HIRA isoform X3

    UniProtKB/TrEMBL
    A0A5F8A9B1
    Related
    ENSMMUP00000074459.1, ENSMMUT00000082322.1
    Conserved Domains (5) summary
    sd00039
    Location:2 → 38
    7WD40; WD40 repeat [structural motif]
    pfam09453
    Location:315 → 336
    HIRA_B; HIRA B motif
    pfam03546
    Location:365 → 585
    Treacle; Treacher Collins syndrome protein Treacle
    pfam07569
    Location:631 → 815
    Hira; TUP1-like enhancer of split
    cl29593
    Location:1 → 218
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein
Heading Accession and Version

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