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MTA2 metastasis associated 1 family member 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 718772, updated on 17-Aug-2024

Summary

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Official Symbol
MTA2provided by VGNC
Official Full Name
metastasis associated 1 family member 2provided by VGNC
Primary source
VGNC:VGNC:74943
Locus tag
EGK_06112
See related
Ensembl:ENSMMUG00000018110
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MTA2 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 14 NC_041767.1 (11601850..11610937)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 14 NC_027906.1 (11711054..11719853)

Chromosome 14 - NC_041767.1Genomic Context describing neighboring genes Neighboring gene beta-1,3-glucuronyltransferase 3 Neighboring gene retinal outer segment membrane protein 1 Neighboring gene EMAP like 3 Neighboring gene uncharacterized LOC106993212 Neighboring gene terminal uridylyl transferase 1, U6 snRNA-specific Neighboring gene uncharacterized LOC106993211 Neighboring gene eukaryotic translation elongation factor 1 gamma

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NuRD complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metastasis-associated protein MTA2
Names
Metastasis-associated 1-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266061.1 → NP_001252990.1  metastasis-associated protein MTA2

    See identical proteins and their annotated locations for NP_001252990.1

    Status: PROVISIONAL

    Source sequence(s)
    JV048690
    UniProtKB/TrEMBL
    A0A8J8YB28, F7EC89, G7NCT9, I0FWD5
    Related
    ENSMMUP00000065614.1, ENSMMUT00000107304.1
    Conserved Domains (6) summary
    cd11661
    Location:267 → 312
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:363 → 414
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    PHA03247
    Location:405 → 664
    PHA03247; large tegument protein UL36; Provisional
    cd04709
    Location:3 → 168
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:147 → 198
    ELM2; ELM2 domain
    pfam17226
    Location:449 → 524
    MTA_R1; MTA R1 domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041767.1 Reference Mmul_10 Primary Assembly

    Range
    11601850..11610937
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028832862.1 → XP_028688695.1  metastasis-associated protein MTA2 isoform X1

    Conserved Domains (4) summary
    cd11661
    Location:94 → 139
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:190 → 241
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    pfam01448
    Location:1 → 25
    ELM2; ELM2 domain
    pfam17226
    Location:276 → 351
    MTA_R1; MTA R1 domain
Nucleotide Protein
Heading Accession and Version

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