MACROD1 mono-ADP ribosylhydrolase 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: MACROD1provided by VGNC
Official Full Name: mono-ADP ribosylhydrolase 1provided by VGNC
Primary source: VGNC:VGNC:107456
See related: Ensembl:ENSMMUG00000056751
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	14	NC_041767.1 (10379282..10551936)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	14	NC_027906.1 (10366665..10539827)

Chromosome 14 - NC_041767.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

SHGC-141828 (e-PCR)
- UniSTS:171101

RH119495 (e-PCR)
- UniSTS:133537

FLRT1__6736 (e-PCR)
- UniSTS:468419

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables ADP-ribosylglutamate hydrolase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA damage response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in peptidyl-glutamate ADP-deribosylation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in purine nucleoside metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: ADP-ribose glycohydrolase MACROD1

Names: MACRO domain containing 1; MACRO domain-containing protein 1

NP_001181614.1

EC 3.1.1.106

XP_014969232.1

EC 3.1.1.106

XP_014969233.1

EC 3.1.1.106

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001194685.1 → NP_001181614.1 ADP-ribose glycohydrolase MACROD1

See identical proteins and their annotated locations for NP_001181614.1

Status: VALIDATED

Source sequence(s)

QNVO02000104

UniProtKB/TrEMBL

A0A5F7ZGM9, A0A5F8APC3

Related

ENSMMUP00000063783.1, ENSMMUT00000080708.1

Conserved Domains (2) summary

COG2110
Location:152 → 314

YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]

cd02908
Location:153 → 319

Macro_Appr_pase_like; Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041767.1 Reference Mmul_10 Primary Assembly

Range

10379282..10551936

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015113746.2 → XP_014969232.1 ADP-ribose glycohydrolase MACROD1 isoform X1

UniProtKB/TrEMBL

A0A5F8APC3

Conserved Domains (2) summary

COG2110
Location:152 → 314

YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]

cd02908
Location:153 → 319

Macro_Appr_pase_like; Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...
XM_015113747.2 → XP_014969233.1 ADP-ribose glycohydrolase MACROD1 isoform X2

UniProtKB/TrEMBL

A0A5F8APC3

Conserved Domains (2) summary

COG2110
Location:152 → 304

YmdB; O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]

cd02908
Location:153 → 309

Macro_Appr_pase_like; Macro domain, Appr-1"-pase_like family. The macro domain is a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose ...