U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MAMU-DOA major histocompatibility complex, class II, DO alpha [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 717947, updated on 5-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
MAMU-DOA
Gene description
major histocompatibility complex, class II, DO alpha
Locus tag
EGK_21541
See related
Ensembl:ENSMMUG00000015734
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See MAMU-DOA in Genome Data Viewer
Location:
chromosome: 4
Exon count:
4
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (136505548..136511316)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (33842149..33845732, complement)

Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene major histocompatibility complex, class II, DP alpha Neighboring gene elongation factor 1-alpha 1 pseudogene Neighboring gene bromodomain containing 2 Neighboring gene major histocompatibility complex, class II, DM alpha

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables MHC class II protein complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in antigen processing and presentation of exogenous peptide antigen via MHC class II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immunoglobulin production involved in immunoglobulin-mediated immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptide antigen assembly with MHC class II protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of T cell activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of MHC class II protein complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
major histocompatibility complex, class II, DO alpha

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001194694.2 → NP_001181623.1  major histocompatibility complex, class II, DO alpha precursor

    See identical proteins and their annotated locations for NP_001181623.1

    Status: PROVISIONAL

    Source sequence(s)
    QNVO02000341
    UniProtKB/TrEMBL
    A0A5F8ADY2, F6S7S7, G8F1Z2
    Related
    ENSMMUP00000075149.1, ENSMMUT00000106785.1
    Conserved Domains (3) summary
    cd05767
    Location:112 → 205
    IgC_MHC_II_alpha; Class II major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    pfam00993
    Location:30 → 108
    MHC_II_alpha; Class II histocompatibility antigen, alpha domain
    pfam16196
    Location:203 → 250
    C1-set_C; C1-set C-terminal domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041757.1 Reference Mmul_10 Primary Assembly

    Range
    136505548..136511316
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015136063.2 → XP_014991549.1  major histocompatibility complex, class II, DO alpha isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZL43, A0A5F8AB71
    Related
    ENSMMUP00000066354.1, ENSMMUT00000109470.1
    Conserved Domains (2) summary
    cd05767
    Location:112 → 204
    IgC_MHC_II_alpha; Class II major histocompatibility complex (MHC) alpha chain immunoglobulin domain
    pfam00993
    Location:30 → 108
    MHC_II_alpha; Class II histocompatibility antigen, alpha domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.