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RGL1 ral guanine nucleotide dissociation stimulator like 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 717554, updated on 17-Aug-2024

Summary

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Official Symbol
RGL1provided by VGNC
Official Full Name
ral guanine nucleotide dissociation stimulator like 1provided by VGNC
Primary source
VGNC:VGNC:76868
Locus tag
EGK_01860
See related
Ensembl:ENSMMUG00000016399
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See RGL1 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
22
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (40896859..41187890)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 1 NC_027893.1 (183330102..183672207, complement)

Chromosome 1 - NC_041754.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114679499 Neighboring gene SMG7 nonsense mediated mRNA decay factor Neighboring gene neutrophil cytosolic factor 2 Neighboring gene actin related protein 2/3 complex subunit 5 Neighboring gene apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4 Neighboring gene uncharacterized LOC114679512 Neighboring gene collagen beta(1-O)galactosyltransferase 2 Neighboring gene tRNA splicing endonuclease subunit 15

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ral guanine nucleotide dissociation stimulator-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266879.1 → NP_001253808.1  ral guanine nucleotide dissociation stimulator-like 1

    See identical proteins and their annotated locations for NP_001253808.1

    Status: PROVISIONAL

    Source sequence(s)
    JU321481
    UniProtKB/TrEMBL
    A0A5F7ZHA5, A0A8J8Y6J3, F7FZA2, G7MF33
    Related
    ENSMMUP00000021538.2, ENSMMUT00000023027.4
    Conserved Domains (3) summary
    smart00229
    Location:100 → 231
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    cd00155
    Location:263 → 532
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cd17210
    Location:682 → 768
    RA_RGL; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1) and similar proteins

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041754.1 Reference Mmul_10 Primary Assembly

    Range
    40896859..41187890
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015121590.2 → XP_014977076.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X3

    UniProtKB/TrEMBL
    A0A5F7ZHA5, A0A5F7ZII8
    Related
    ENSMMUP00000064995.1, ENSMMUT00000090691.1
    Conserved Domains (3) summary
    cd00153
    Location:646 → 731
    RalGDS_RA; Ubiquitin domain of RalGDS-like factor (RLF) and related proteins
    smart00229
    Location:63 → 194
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    cd00155
    Location:226 → 495
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  2. XM_028845858.1 → XP_028701691.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZHA5, A0A8J8Y6J3, F7FZA2, G7MF33
    Conserved Domains (3) summary
    smart00229
    Location:100 → 231
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    cd00155
    Location:263 → 532
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cd17210
    Location:682 → 768
    RA_RGL; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1) and similar proteins

  3. XM_028845860.1 → XP_028701693.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZHA5, A0A8J8Y6J3, F7FZA2, G7MF33
    Related
    ENSMMUP00000064014.1, ENSMMUT00000104072.1
    Conserved Domains (3) summary
    smart00229
    Location:100 → 231
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    cd00155
    Location:263 → 532
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cd17210
    Location:682 → 768
    RA_RGL; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator-like 1 (RalGDS-like 1) and similar proteins

  4. XM_015121585.2 → XP_014977071.1  ral guanine nucleotide dissociation stimulator-like 1 isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZHA5, F7FYX4
    Related
    ENSMMUP00000021540.2, ENSMMUT00000023029.4
    Conserved Domains (3) summary
    cd00153
    Location:648 → 733
    RalGDS_RA; Ubiquitin domain of RalGDS-like factor (RLF) and related proteins
    smart00229
    Location:65 → 196
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    cd00155
    Location:228 → 497
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
Nucleotide Protein
Heading Accession and Version

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