OXT oxytocin/neurophysin I prepropeptide [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: OXTprovided by VGNC
Official Full Name: oxytocin/neurophysin I prepropeptideprovided by VGNC
Primary source: VGNC:VGNC:75730
See related: Ensembl:ENSMMUG00000010678
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 10

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	10	NC_041763.1 (63431425..63432796, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	10	NC_027902.1 (35900674..35901743)

Chromosome 10 - NC_041763.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Methylation of OXT and OXTR genes, central oxytocin, and social behavior in female macaques.
Title: Methylation of OXT and OXTR genes, central oxytocin, and social behavior in female macaques.
Treating a group of male macaque monkeys intranasally with aerosolized oxytocin relaxes their spontaneous social interactions with other monkeys. Oxytocin reduces differences in social behavior between dominant and subordinate monkeys, thereby flattening the status hierarchy.
Title: Oxytocin and vasopressin flatten dominance hierarchy and enhance behavioral synchrony in part via anterior cingulate cortex.
These results argue that central oxytocin biology may be related to individual face perceptual abilities necessary for group living, and that these differences are stable traits.
Title: Preference for novel faces in male infant monkeys predicts cerebrospinal fluid oxytocin concentrations later in life.
Intranasal oxytocin reduced monkeys' attention to negative facial expressions, but not neutral faces or clip art, and enhanced monkeys' attention to direct vs. averted gaze faces. Rhesus monkey social perception is mediated by the oxytocinergic system.
Title: Intranasal oxytocin selectively attenuates rhesus monkeys' attention to negative facial expressions.
Females possessing the G allele for mu-opioid receptor 1 also show higher oxytocin levels when lactating, and lower oxytocin levels when neither lactating nor pregnant, than females homozygous for the C allele.
Title: Mu-opioid receptor (OPRM1) variation, oxytocin levels and maternal attachment in free-ranging rhesus macaques Macaca mulatta.
findings: 1) provide feasibility data for examining CSF oxytocin levels in free-ranging non-human primates and 2) indicate that CSF oxytocin levels may be a biomarker of age-related central nervous system changes across lifespan development
Title: Effects of age on cerebrospinal fluid oxytocin levels in free-ranging adult female and infant rhesus macaques.

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

RH64825 (e-PCR)
- UniSTS:68900

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables neurohypophyseal hormone activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed
located_in secretory granule	IEA Inferred from Electronic Annotation more info	PubMed