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MELK maternal embryonic leucine zipper kinase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716875, updated on 17-Aug-2024

Summary

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Official Symbol
MELKprovided by VGNC
Official Full Name
maternal embryonic leucine zipper kinaseprovided by VGNC
Primary source
VGNC:VGNC:74521
See related
Ensembl:ENSMMUG00000003782
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See MELK in Genome Data Viewer
Location:
chromosome: 15
Exon count:
19
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 15 NC_041768.1 (47469371..47589700, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 15 NC_027907.1 (47477135..47598507, complement)

Chromosome 15 - NC_041768.1Genomic Context describing neighboring genes Neighboring gene paired box 5 Neighboring gene uncharacterized LOC100427249 Neighboring gene 60S ribosomal protein L23a Neighboring gene ring finger protein 38 Neighboring gene uncharacterized LOC114672764

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tau-protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in microtubule cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
maternal embryonic leucine zipper kinase
XP_014972914.2
XP_014972915.2
XP_028690886.1
XP_028690887.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041768.1 Reference Mmul_10 Primary Assembly

    Range
    47469371..47589700 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015117429.2 → XP_014972915.2  maternal embryonic leucine zipper kinase isoform X1

    UniProtKB/TrEMBL
    A0A1D5QDI7, H9Z026, I2CVB0
    Related
    ENSMMUP00000046106.2, ENSMMUT00000067938.2
    Conserved Domains (3) summary
    cd12198
    Location:555 → 649
    MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
    cd14341
    Location:281 → 332
    UBA_MELK; UBA domain found in maternal embryonic leucine zipper kinase (MELK) and similar proteins
    cd14078
    Location:7 → 263
    STKc_MELK; Catalytic domain of the Serine/Threonine Kinase, Maternal Embryonic Leucine zipper Kinase

  2. XM_028835054.1 → XP_028690887.1  maternal embryonic leucine zipper kinase isoform X2

    UniProtKB/TrEMBL
    H9Z026
    Conserved Domains (2) summary
    cd12198
    Location:526 → 620
    MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
    cd14078
    Location:7 → 263
    STKc_MELK; Catalytic domain of the Serine/Threonine Kinase, Maternal Embryonic Leucine zipper Kinase

  3. XM_028835053.1 → XP_028690886.1  maternal embryonic leucine zipper kinase isoform X1

    UniProtKB/TrEMBL
    A0A1D5QDI7, H9Z026, I2CVB0
    Conserved Domains (3) summary
    cd12198
    Location:555 → 649
    MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
    cd14341
    Location:281 → 332
    UBA_MELK; UBA domain found in maternal embryonic leucine zipper kinase (MELK) and similar proteins
    cd14078
    Location:7 → 263
    STKc_MELK; Catalytic domain of the Serine/Threonine Kinase, Maternal Embryonic Leucine zipper Kinase

  4. XM_015117428.2 → XP_014972914.2  maternal embryonic leucine zipper kinase isoform X1

    UniProtKB/TrEMBL
    A0A1D5QDI7, H9Z026, I2CVB0
    Conserved Domains (3) summary
    cd12198
    Location:555 → 649
    MELK_C; C-terminal kinase associated domain 1 (KA1) of Maternal embryonic leucine zipper kinase
    cd14341
    Location:281 → 332
    UBA_MELK; UBA domain found in maternal embryonic leucine zipper kinase (MELK) and similar proteins
    cd14078
    Location:7 → 263
    STKc_MELK; Catalytic domain of the Serine/Threonine Kinase, Maternal Embryonic Leucine zipper Kinase
Nucleotide Protein
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