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HTR1B 5-hydroxytryptamine receptor 1B [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716704, updated on 17-Aug-2024

Summary

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Official Symbol
HTR1Bprovided by VGNC
Official Full Name
5-hydroxytryptamine receptor 1Bprovided by VGNC
Primary source
VGNC:VGNC:73537
Locus tag
EGK_15097
See related
Ensembl:ENSMMUG00000015717
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See HTR1B in Genome Data Viewer
Location:
chromosome: 4
Exon count:
1
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (95570257..95575433)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (75618402..75623579, complement)

Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene ubiquitin-conjugating enzyme E2 C-like Neighboring gene meiotic double-stranded break formation protein 4 Neighboring gene uncharacterized LOC114677397 Neighboring gene 52 kDa repressor of the inhibitor of the protein kinase-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses. Watakabe A, et al. Cereb Cortex, 2009 Aug. PMID 19056862, Free PMC Article
  2. Distribution of 5-HT1B and 5-HT1D receptors in the inner ear. Ahn SK, et al. Brain Res, 2010 Jul 30. PMID 20510890, Free PMC Article
  3. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. vestibular ganglion cells were immunoreactive for 5-HT(1B) receptors in macaques and rats.
    Title: Distribution of 5-HT1B and 5-HT1D receptors in the inner ear.
  2. found high levels of serotonin receptor 1B mRNA in primary visual cortex (V1) and clear activity-dependent modulatory effects of 5-HT1B receptor agonists on responses of V1 neurons.
    Title: Enriched expression of serotonin 1B and 2A receptor genes in macaque visual cortex and their bidirectional modulatory effects on neuronal responses.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled serotonin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in adenylate cyclase-activating adrenergic receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in bone remodeling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of behavior IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vasoconstriction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5-hydroxytryptamine receptor 1B
Names
serotonin receptor type 1B

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041757.1 Reference Mmul_10 Primary Assembly

    Range
    95570257..95575433
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015136810.2 → XP_014992296.1  5-hydroxytryptamine receptor 1B

    UniProtKB/TrEMBL
    A0A8J8XEK3, F6SFA9, G7MPS2, X2CFC5
    Related
    ENSMMUP00000020635.2, ENSMMUT00000022058.4
    Conserved Domains (1) summary
    cd15333
    Location:46 → 380
    7tmA_5-HT1B_1D; serotonin receptor subtypes 1B and 1D, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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