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MYO6 myosin VI [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716634, updated on 17-Aug-2024

Summary

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Official Symbol
MYO6provided by VGNC
Official Full Name
myosin VIprovided by VGNC
Primary source
VGNC:VGNC:75118
See related
Ensembl:ENSMMUG00000005032
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as
myosin-VI
Orthologs
human mouse all
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Genomic context

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See MYO6 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
37
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (97096230..97260374, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (73865975..74037622)

Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene interphotoreceptor matrix proteoglycan 1 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC114677561 Neighboring gene SUMO specific peptidase 6 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microfilament motor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inner ear auditory receptor cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inner ear morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in vesicle transport along actin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endocytic vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of myosin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in ruffle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
unconventional myosin-VI

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001104536.1 → NP_001098006.1  unconventional myosin-VI

    See identical proteins and their annotated locations for NP_001098006.1

    Status: PROVISIONAL

    Source sequence(s)
    EU073749
    UniProtKB/TrEMBL
    A7XBL5, G7MPR9
    Conserved Domains (3) summary
    smart00242
    Location:52 → 771
    MYSc; Myosin. Large ATPases
    cd01382
    Location:71 → 759
    MYSc_Myo6; class VI myosin, motor domain
    pfam16521
    Location:1136 → 1226
    Myosin-VI_CBD; Myosin VI cargo binding domain

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041757.1 Reference Mmul_10 Primary Assembly

    Range
    97096230..97260374 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015136777.2 → XP_014992263.1  unconventional myosin-VI isoform X8

    UniProtKB/TrEMBL
    G7MPR9
    Conserved Domains (3) summary
    smart00242
    Location:52 → 771
    MYSc; Myosin. Large ATPases
    cd01382
    Location:71 → 759
    MYSc_Myo6; class VI myosin, motor domain
    pfam16521
    Location:1145 → 1235
    Myosin-VI_CBD; Myosin VI cargo binding domain

  2. XM_015136778.2 → XP_014992264.1  unconventional myosin-VI isoform X9

    UniProtKB/TrEMBL
    A0A1D5QGD8, G7MPR9
    Related
    ENSMMUP00000047108.2, ENSMMUT00000072194.2
    Conserved Domains (3) summary
    smart00242
    Location:52 → 771
    MYSc; Myosin. Large ATPases
    cd01382
    Location:71 → 759
    MYSc_Myo6; class VI myosin, motor domain
    pfam16521
    Location:1136 → 1226
    Myosin-VI_CBD; Myosin VI cargo binding domain

  3. XM_015136776.2 → XP_014992262.1  unconventional myosin-VI isoform X7

    UniProtKB/TrEMBL
    G7MPR9
    Conserved Domains (3) summary
    smart00242
    Location:52 → 771
    MYSc; Myosin. Large ATPases
    cd01382
    Location:71 → 759
    MYSc_Myo6; class VI myosin, motor domain
    pfam16521
    Location:1155 → 1245
    Myosin-VI_CBD; Myosin VI cargo binding domain

  4. XM_015136775.2 → XP_014992261.1  unconventional myosin-VI isoform X5

    UniProtKB/TrEMBL
    G7MPR9
    Conserved Domains (3) summary
    smart00242
    Location:52 → 771
    MYSc; Myosin. Large ATPases
    cd01382
    Location:71 → 759
    MYSc_Myo6; class VI myosin, motor domain
    pfam16521
    Location:1159 → 1249
    Myosin-VI_CBD; Myosin VI cargo binding domain

  5. XM_015136773.2 → XP_014992259.1  unconventional myosin-VI isoform X3

    UniProtKB/TrEMBL
    F7ARX1, G7MPR9
    Related
    ENSMMUP00000006662.4, ENSMMUT00000007091.4
    Conserved Domains (4) summary
    cd01382
    Location:71 → 759
    MYSc_Myo6; class VI myosin, motor domain
    pfam05835
    Location:980 → 1055
    Synaphin; Synaphin protein
    pfam16521
    Location:1168 → 1258
    Myosin-VI_CBD; Myosin VI cargo binding domain
    cl25732
    Location:846 → 1134
    SMC_N; RecF/RecN/SMC N terminal domain

  6. XM_028846843.1 → XP_028702676.1  unconventional myosin-VI isoform X6

    UniProtKB/TrEMBL
    G7MPR9
    Conserved Domains (2) summary
    cd01382
    Location:71 → 759
    MYSc_Myo6; class VI myosin, motor domain
    pfam16521
    Location:1155 → 1245
    Myosin-VI_CBD; Myosin VI cargo binding domain

  7. XM_015136774.2 → XP_014992260.1  unconventional myosin-VI isoform X4

    UniProtKB/TrEMBL
    G7MPR9
    Conserved Domains (3) summary
    smart00242
    Location:52 → 771
    MYSc; Myosin. Large ATPases
    cd01382
    Location:71 → 759
    MYSc_Myo6; class VI myosin, motor domain
    pfam16521
    Location:1164 → 1254
    Myosin-VI_CBD; Myosin VI cargo binding domain

  8. XM_015136772.2 → XP_014992258.1  unconventional myosin-VI isoform X2

    UniProtKB/TrEMBL
    G7MPR9
    Conserved Domains (3) summary
    smart00242
    Location:52 → 771
    MYSc; Myosin. Large ATPases
    cd01382
    Location:71 → 759
    MYSc_Myo6; class VI myosin, motor domain
    pfam16521
    Location:1168 → 1258
    Myosin-VI_CBD; Myosin VI cargo binding domain

  9. XM_015136770.2 → XP_014992256.1  unconventional myosin-VI isoform X1

    UniProtKB/TrEMBL
    G7MPR9
    Conserved Domains (4) summary
    cd01382
    Location:71 → 759
    MYSc_Myo6; class VI myosin, motor domain
    pfam16521
    Location:1177 → 1267
    Myosin-VI_CBD; Myosin VI cargo binding domain
    cd21759
    Location:770 → 917
    CBD_MYO6-like; calmodulin binding domain found in unconventional myosin-VI and similar proteins
    cd22294
    Location:999 → 1068
    MYO6_MIU_linker; MIU-linker domain found in unconventional myosin-VI

  10. XM_028846844.1 → XP_028702677.1  unconventional myosin-VI isoform X10

    UniProtKB/TrEMBL
    G7MPR9
    Conserved Domains (2) summary
    pfam16521
    Location:930 → 1020
    Myosin-VI_CBD; Myosin VI cargo binding domain
    cl22853
    Location:3 → 512
    Motor_domain; Myosin and Kinesin motor domain

  11. XM_015136771.2 → XP_014992257.1  unconventional myosin-VI isoform X1

    UniProtKB/TrEMBL
    G7MPR9
    Conserved Domains (4) summary
    cd01382
    Location:71 → 759
    MYSc_Myo6; class VI myosin, motor domain
    pfam16521
    Location:1177 → 1267
    Myosin-VI_CBD; Myosin VI cargo binding domain
    cd21759
    Location:770 → 917
    CBD_MYO6-like; calmodulin binding domain found in unconventional myosin-VI and similar proteins
    cd22294
    Location:999 → 1068
    MYO6_MIU_linker; MIU-linker domain found in unconventional myosin-VI
Nucleotide Protein
Heading Accession and Version

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