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ROS1 ROS proto-oncogene 1, receptor tyrosine kinase [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 715284, updated on 11-Apr-2024

Summary

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Gene symbol
ROS1
Gene description
ROS proto-oncogene 1, receptor tyrosine kinase
See related
Ensembl:ENSMMUG00000023738
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See ROS1 in Genome Data Viewer
Location:
chromosome: 4
Exon count:
43
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (20806887..20949952, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (150449976..150592891)

Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene regulatory factor X6 Neighboring gene vestigial like family member 2 Neighboring gene ras-related protein Rap-1b-like Neighboring gene peptidyl-prolyl cis-trans isomerase A pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of TOR signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
proto-oncogene tyrosine-protein kinase ROS
Names
c-ros oncogene 1 , receptor tyrosine kinase
v-ros UR2 sarcoma virus oncogene homolog 1
XP_028702889.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041757.1 Reference Mmul_10 Primary Assembly

    Range
    20806887..20949952 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028847056.1 → XP_028702889.1  proto-oncogene tyrosine-protein kinase ROS

    UniProtKB/TrEMBL
    F7FRT8
    Related
    ENSMMUP00000033054.3, ENSMMUT00000039989.3
    Conserved Domains (3) summary
    smart00060
    Location:102 → 169
    FN3; Fibronectin type 3 domain
    cd00063
    Location:202 → 281
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05044
    Location:1948 → 2214
    PTKc_c-ros; Catalytic domain of the Protein Tyrosine Kinase, C-ros
Nucleotide Protein
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