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DGKB diacylglycerol kinase beta [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 715254, updated on 18-Sep-2024

Summary

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Official Symbol
DGKBprovided by VGNC
Official Full Name
diacylglycerol kinase betaprovided by VGNC
Primary source
VGNC:VGNC:71782
See related
Ensembl:ENSMMUG00000020418
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DGKB in Genome Data Viewer
Location:
chromosome: 3
Exon count:
29
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (100092594..100860322)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (89982917..90748180, complement)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene alkylglycerol monooxygenase Neighboring gene transcription factor IIIA pseudogene Neighboring gene uncharacterized LOC106997506 Neighboring gene uncharacterized LOC106997507 Neighboring gene myosin, light chain 6, alkali, smooth muscle and non-muscle-like Neighboring gene 60S ribosomal protein L6 pseudogene Neighboring gene ETS variant transcription factor 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP-dependent diacylglycerol kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in diacylglycerol metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lipid phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
diacylglycerol kinase beta
XP_014989402.1
XP_014989403.1
XP_014989404.1
XP_014989405.1
XP_014989406.1
XP_014989407.1
XP_014989408.1
XP_014989409.1
XP_014989411.1
XP_028701829.1
XP_028701831.1
XP_028701832.1
XP_028701833.1
XP_028701834.1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    100092594..100860322
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015133916.2 → XP_014989402.1  diacylglycerol kinase beta isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZBC6, I2CTX4
    Related
    ENSMMUP00000061925.1, ENSMMUT00000108317.1
    Conserved Domains (8) summary
    smart00045
    Location:582 → 762
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:440 → 561
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:440 → 772
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00029
    Location:245 → 294
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:153 → 222
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:310 → 361
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:154 → 218
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:6 → 149
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  2. XM_015133918.2 → XP_014989404.1  diacylglycerol kinase beta isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZBC6, F6U0I9, H9FQL9
    Related
    ENSMMUP00000026871.4, ENSMMUT00000028718.4
    Conserved Domains (6) summary
    smart00045
    Location:581 → 761
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:439 → 560
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:153 → 222
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:6 → 149
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20845
    Location:238 → 303
    C1_DGKbeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins
    cd20891
    Location:308 → 366
    C1_DGKbeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins

  3. XM_015133921.2 → XP_014989407.1  diacylglycerol kinase beta isoform X5

    UniProtKB/TrEMBL
    A0A5F7ZBC6
    Conserved Domains (6) summary
    smart00045
    Location:570 → 750
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:428 → 549
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:153 → 222
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:6 → 149
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20845
    Location:238 → 303
    C1_DGKbeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins
    cd20891
    Location:308 → 366
    C1_DGKbeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins

  4. XM_015133919.2 → XP_014989405.1  diacylglycerol kinase beta isoform X3

    UniProtKB/TrEMBL
    A0A5F7ZBC6
    Conserved Domains (6) summary
    smart00045
    Location:575 → 755
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:433 → 554
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:146 → 215
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:6 → 142
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20845
    Location:231 → 296
    C1_DGKbeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins
    cd20891
    Location:301 → 359
    C1_DGKbeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins

  5. XM_015133920.2 → XP_014989406.1  diacylglycerol kinase beta isoform X4

    UniProtKB/TrEMBL
    A0A5F7ZBC6, H9FQL5
    Conserved Domains (6) summary
    smart00045
    Location:574 → 754
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:432 → 553
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:146 → 215
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:6 → 142
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20845
    Location:231 → 296
    C1_DGKbeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins
    cd20891
    Location:301 → 359
    C1_DGKbeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins

  6. XM_015133922.2 → XP_014989408.1  diacylglycerol kinase beta isoform X6

    UniProtKB/TrEMBL
    A0A5F7ZBC6, A0A5F8A472
    Conserved Domains (8) summary
    smart00045
    Location:563 → 743
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:421 → 542
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:421 → 753
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00029
    Location:238 → 287
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:146 → 215
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:303 → 354
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:147 → 211
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:6 → 142
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  7. XM_028845996.1 → XP_028701829.1  diacylglycerol kinase beta isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZBC6, F6U0I9, H9FQL9
    Conserved Domains (6) summary
    smart00045
    Location:581 → 761
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:439 → 560
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:153 → 222
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:6 → 149
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20845
    Location:238 → 303
    C1_DGKbeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins
    cd20891
    Location:308 → 366
    C1_DGKbeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins

  8. XM_015133917.2 → XP_014989403.1  diacylglycerol kinase beta isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZBC6, I2CTX4
    Conserved Domains (8) summary
    smart00045
    Location:582 → 762
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:440 → 561
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:440 → 772
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00029
    Location:245 → 294
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:153 → 222
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:310 → 361
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:154 → 218
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:6 → 149
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  9. XM_028846000.1 → XP_028701833.1  diacylglycerol kinase beta isoform X5

    UniProtKB/TrEMBL
    A0A5F7ZBC6
    Conserved Domains (6) summary
    smart00045
    Location:570 → 750
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:428 → 549
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:153 → 222
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:6 → 149
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20845
    Location:238 → 303
    C1_DGKbeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins
    cd20891
    Location:308 → 366
    C1_DGKbeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins

  10. XM_028845998.1 → XP_028701831.1  diacylglycerol kinase beta isoform X3

    UniProtKB/TrEMBL
    A0A5F7ZBC6
    Conserved Domains (6) summary
    smart00045
    Location:575 → 755
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:433 → 554
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:146 → 215
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:6 → 142
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20845
    Location:231 → 296
    C1_DGKbeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins
    cd20891
    Location:301 → 359
    C1_DGKbeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins

  11. XM_015133923.2 → XP_014989409.1  diacylglycerol kinase beta isoform X6

    UniProtKB/TrEMBL
    A0A5F7ZBC6, A0A5F8A472
    Related
    ENSMMUP00000071702.1, ENSMMUT00000100885.1
    Conserved Domains (8) summary
    smart00045
    Location:563 → 743
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:421 → 542
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:421 → 753
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00029
    Location:238 → 287
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:146 → 215
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:303 → 354
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:147 → 211
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:6 → 142
    DAG_kinase_N; Diacylglycerol kinase N-terminus

  12. XM_028845999.1 → XP_028701832.1  diacylglycerol kinase beta isoform X4

    UniProtKB/TrEMBL
    A0A5F7ZBC6, H9FQL5
    Conserved Domains (6) summary
    smart00045
    Location:574 → 754
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:432 → 553
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:146 → 215
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:6 → 142
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20845
    Location:231 → 296
    C1_DGKbeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins
    cd20891
    Location:301 → 359
    C1_DGKbeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins

  13. XM_028846001.1 → XP_028701834.1  diacylglycerol kinase beta isoform X7

    UniProtKB/TrEMBL
    A0A5F7ZBC6
    Conserved Domains (6) summary
    smart00046
    Location:440 → 561
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    cd00051
    Location:153 → 222
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam14513
    Location:6 → 149
    DAG_kinase_N; Diacylglycerol kinase N-terminus
    cd20845
    Location:238 → 303
    C1_DGKbeta_rpt1; first protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins
    cd20891
    Location:308 → 366
    C1_DGKbeta_rpt2; second protein kinase C conserved region 1 (C1 domain) found in diacylglycerol kinase beta (DAG kinase beta) and similar proteins
    cl02440
    Location:582 → 679
    DAGK_acc; Diacylglycerol kinase accessory domain

  14. XM_015133925.2 → XP_014989411.1  diacylglycerol kinase beta isoform X8

    UniProtKB/TrEMBL
    G7MLS2
    Conserved Domains (8) summary
    smart00045
    Location:472 → 652
    DAGKa; Diacylglycerol kinase accessory domain (presumed)
    smart00046
    Location:330 → 451
    DAGKc; Diacylglycerol kinase catalytic domain (presumed)
    COG1597
    Location:330 → 662
    LCB5; Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only]
    cd00029
    Location:135 → 184
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    cd00051
    Location:43 → 112
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
    pfam00130
    Location:200 → 251
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
    pfam13499
    Location:44 → 108
    EF-hand_7; EF-hand domain pair
    pfam14513
    Location:3 → 39
    DAG_kinase_N; Diacylglycerol kinase N-terminus
Nucleotide Protein
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