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SH2B2 SH2B adaptor protein 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 714861, updated on 17-Aug-2024

Summary

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Official Symbol
SH2B2provided by VGNC
Official Full Name
SH2B adaptor protein 2provided by VGNC
Primary source
VGNC:VGNC:77257
See related
Ensembl:ENSMMUG00000010329
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See SH2B2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
11
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (44437451..44476438)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (127714271..127753479)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene cut like homeobox 1 Neighboring gene small nucleolar RNA SNORA48 Neighboring gene uncharacterized LOC106997589 Neighboring gene PRKR interacting protein 1 Neighboring gene ORAI calcium release-activated calcium modulator 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transmembrane receptor protein tyrosine kinase adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in antigen receptor-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SH2B adapter protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    44437451..44476438
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015134545.2 → XP_014990031.2  SH2B adapter protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A5F7ZD61, F6RGT3
    Related
    ENSMMUP00000013535.4, ENSMMUT00000014448.4
    Conserved Domains (3) summary
    cd10411
    Location:456 → 551
    SH2_SH2B2; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:240 → 355
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:65 → 121
    Phe_ZIP; Phenylalanine zipper

  2. XM_028845622.1 → XP_028701455.1  SH2B adapter protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZAQ9, A0A5F7ZD61
    Conserved Domains (3) summary
    cd10411
    Location:413 → 508
    SH2_SH2B2; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:197 → 312
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:22 → 78
    Phe_ZIP; Phenylalanine zipper

  3. XM_028845624.1 → XP_028701457.1  SH2B adapter protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A5F7ZD61
    Conserved Domains (3) summary
    cd10411
    Location:412 → 507
    SH2_SH2B2; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:197 → 312
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:22 → 78
    Phe_ZIP; Phenylalanine zipper

  4. XM_028845623.1 → XP_028701456.1  SH2B adapter protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A5F7ZAQ9, A0A5F7ZD61
    Related
    ENSMMUP00000062683.1, ENSMMUT00000083747.1
    Conserved Domains (3) summary
    cd10411
    Location:413 → 508
    SH2_SH2B2; Src homology 2 (SH2) domain found in SH2B adapter proteins (SH2B1, SH2B2, SH2B3)
    cd01231
    Location:197 → 312
    PH_SH2B_family; SH2B adapter protein 1, 2, and 3 Pleckstrin homology (PH) domain
    pfam08916
    Location:22 → 78
    Phe_ZIP; Phenylalanine zipper
Nucleotide Protein
Heading Accession and Version

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