FBN1 fibrillin 1 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: FBN1provided by VGNC
Official Full Name: fibrillin 1provided by VGNC
Primary source: VGNC:VGNC:72623
See related: Ensembl:ENSMMUG00000004239
Gene type: protein coding
RefSeq status: MODEL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 67

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	7	NC_041760.1 (24826757..25063635, complement)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	7	NC_027899.1 (24728654..24967095, complement)

Chromosome 7 - NC_041760.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The synthetic expression of FBN 1 declined with aging in monkey's eyes.
Title: Intracapsular organization of ciliary zonules in monkey eyes.

Submit: New GeneRIF Correction

General gene information

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Markers

GDB:455155 (e-PCR)
- UniSTS:157454

GDB:455176 (e-PCR)
- UniSTS:157455

SHGC-81440 (e-PCR)
- UniSTS:103195

G64181 (e-PCR)
- UniSTS:146719

G64182 (e-PCR)
- UniSTS:146720

G64177 (e-PCR)
- UniSTS:146721

G64179 (e-PCR)
- UniSTS:146724

G63904 (e-PCR)
- UniSTS:146480

G63892 (e-PCR)
- UniSTS:146481

G63902 (e-PCR)
- UniSTS:146482

G63901 (e-PCR)
- UniSTS:146483

SHGC-56864 (e-PCR)
- UniSTS:64313

GDB:636540 (e-PCR)
- UniSTS:158547

G64963 (e-PCR)
- UniSTS:164953

D15S1255 (e-PCR)
- UniSTS:69980

G64973 (e-PCR)
- UniSTS:164957

G64970 (e-PCR)
- UniSTS:164959

G64969 (e-PCR)
- UniSTS:164960

GDB:438900 (e-PCR)
- UniSTS:157282

G64966 (e-PCR)
- UniSTS:164963

G64968 (e-PCR)
- UniSTS:164964

G64936 (e-PCR)
- UniSTS:164965

G64942 (e-PCR)
- UniSTS:164966

G64947 (e-PCR)
- UniSTS:164971

G64950 (e-PCR)
- UniSTS:164974

Fbn1 (e-PCR), detects polymorphism
- UniSTS:531311

G64995 (e-PCR)
- UniSTS:164976

G64937 (e-PCR)
- UniSTS:164977

G17855 (e-PCR)
- UniSTS:20118

D15S196 (e-PCR), detects polymorphism
- UniSTS:43450

G65329 (e-PCR)
- UniSTS:166341

WI-18561 (e-PCR)
- UniSTS:21704

G60567 (e-PCR)
- UniSTS:137673

G65298 (e-PCR)
- UniSTS:166347

G65296 (e-PCR)
- UniSTS:166349

G65330 (e-PCR)
- UniSTS:166351

G65289 (e-PCR)
- UniSTS:166352

G65302 (e-PCR)
- UniSTS:166356

G65281 (e-PCR)
- UniSTS:166359

GDB:190047 (e-PCR)
- UniSTS:155615

GDB:190048 (e-PCR)
- UniSTS:155616

Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: fibrillin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041760.1 Reference Mmul_10 Primary Assembly

Range

24826757..25063635 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_015142182.2 → XP_014997668.1 fibrillin-1

UniProtKB/TrEMBL

A0A1D5Q4D3, F6YVP3, I0FJ04

Related

ENSMMUP00000005670.4, ENSMMUT00000006025.4

Conserved Domains (9) summary

smart00179
Location:1808 → 1840

EGF_CA; Calcium-binding EGF-like domain

cd00054
Location:765 → 806

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

pfam07645
Location:1930 → 1971

EGF_CA; Calcium-binding EGF domain

pfam00683
Location:1549 → 1590

TB; TB domain

pfam12662
Location:2465 → 2488

cEGF; Complement Clr-like EGF-like

pfam12947
Location:1367 → 1402

EGF_3; EGF domain

pfam18193
Location:48 → 82

Fibrillin_U_N; Fibrillin 1 unique N-terminal domain

cl00057
Location:1194 → 1235

vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

cl21504
Location:2485 → 2516

EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...