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DVL2 dishevelled segment polarity protein 2 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 714381, updated on 17-Aug-2024

Summary

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Official Symbol
DVL2provided by VGNC
Official Full Name
dishevelled segment polarity protein 2provided by VGNC
Primary source
VGNC:VGNC:104598
Locus tag
EGK_08107
See related
Ensembl:ENSMMUG00000052091
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See DVL2 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
15
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (6992741..7002043, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (7201810..7211484, complement)

Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene discs large MAGUK scaffold protein 4 Neighboring gene acyl-CoA dehydrogenase very long chain Neighboring gene microRNA mir-324 Neighboring gene PHD finger protein 23 Neighboring gene GABA type A receptor-associated protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables frizzled binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
segment polarity protein dishevelled homolog DVL-2
Names
Segment polarity protein dishevelled-like protein DVL-2
dishevelled, dsh homolog 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001194806.2 → NP_001181735.1  segment polarity protein dishevelled homolog DVL-2

    Status: PROVISIONAL

    Source sequence(s)
    QNVO02000155
    UniProtKB/TrEMBL
    H9Z606, I0FPQ7
    Related
    ENSMMUP00000061251.1, ENSMMUT00000094955.1
    Conserved Domains (5) summary
    smart00021
    Location:13 → 93
    DAX; Domain present in Dishevelled and axin
    cd00992
    Location:259 → 346
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd04438
    Location:418 → 501
    DEP_dishevelled; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in dishevelled-like proteins. Dishevelled-like proteins play a key role in the transduction of the Wnt signal from the cell surface to the nucleus, which in turn is an important regulatory pathway ...
    pfam02377
    Location:125 → 257
    Dishevelled; Dishevelled specific domain
    pfam12316
    Location:509 → 720
    Dsh_C; Segment polarity protein dishevelled (Dsh) C terminal

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041769.1 Reference Mmul_10 Primary Assembly

    Range
    6992741..7002043 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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Molecular Biology Databases
Research Materials