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STAT6 signal transducer and activator of transcription 6 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 714159, updated on 17-Aug-2024

Summary

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Official Symbol
STAT6provided by VGNC
Official Full Name
signal transducer and activator of transcription 6provided by VGNC
Primary source
VGNC:VGNC:77908
See related
Ensembl:ENSMMUG00000017527
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See STAT6 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
28
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 11 NC_041764.1 (56652940..56675153, complement)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (55866972..55889199, complement)

Chromosome 11 - NC_041764.1Genomic Context describing neighboring genes Neighboring gene nuclear envelope integral membrane protein 1 Neighboring gene uncharacterized LOC114670870 Neighboring gene basic proline-rich protein Neighboring gene NGFI-A binding protein 2 Neighboring gene LDL receptor related protein 1 Neighboring gene neurexophilin 4

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001265997.1 → NP_001252926.1  signal transducer and activator of transcription 6

    See identical proteins and their annotated locations for NP_001252926.1

    Status: PROVISIONAL

    Source sequence(s)
    JV635568
    UniProtKB/TrEMBL
    A0A8J8YKC5, F6UMM2, G7N7E9, H9YVW6, I2CVC3
    Related
    ENSMMUP00000023071.4, ENSMMUT00000024650.4
    Conserved Domains (5) summary
    cd10377
    Location:517 → 646
    SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
    smart00964
    Location:2 → 115
    STAT_int; STAT protein, protein interaction domain
    pfam01017
    Location:124 → 271
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:273 → 526
    STAT_bind; STAT protein, DNA binding domain
    pfam14596
    Location:655 → 847
    STAT6_C; STAT6 C-terminal

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041764.1 Reference Mmul_10 Primary Assembly

    Range
    56652940..56675153 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015152044.2 → XP_015007530.1  signal transducer and activator of transcription 6 isoform X1

    UniProtKB/TrEMBL
    A0A8J8YKC5, F6UMM2, G7N7E9, H9YVW6, I2CVC3
    Related
    ENSMMUP00000073990.1, ENSMMUT00000108000.1
    Conserved Domains (5) summary
    cd10377
    Location:517 → 646
    SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
    smart00964
    Location:2 → 115
    STAT_int; STAT protein, protein interaction domain
    pfam01017
    Location:124 → 271
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:273 → 526
    STAT_bind; STAT protein, DNA binding domain
    pfam14596
    Location:655 → 847
    STAT6_C; STAT6 C-terminal

  2. XM_015152045.2 → XP_015007531.1  signal transducer and activator of transcription 6 isoform X1

    UniProtKB/TrEMBL
    A0A8J8YKC5, F6UMM2, G7N7E9, H9YVW6, I2CVC3
    Related
    ENSMMUP00000069419.1, ENSMMUT00000110291.1
    Conserved Domains (5) summary
    cd10377
    Location:517 → 646
    SH2_STAT6; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 6 proteins
    smart00964
    Location:2 → 115
    STAT_int; STAT protein, protein interaction domain
    pfam01017
    Location:124 → 271
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:273 → 526
    STAT_bind; STAT protein, DNA binding domain
    pfam14596
    Location:655 → 847
    STAT6_C; STAT6 C-terminal
Nucleotide Protein
Heading Accession and Version

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