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AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 714140, updated on 17-Aug-2024

Summary

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Official Symbol
AGAP3provided by VGNC
Official Full Name
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3provided by VGNC
Primary source
VGNC:VGNC:69621
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See AGAP3 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
21
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 3 NC_041756.1 (177089081..177145799)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 3 NC_027895.1 (177308227..177365307)

Chromosome 3 - NC_041756.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 4 member 2 Neighboring gene Fas activated serine/threonine kinase Neighboring gene transmembrane and ubiquitin like domain containing 1 Neighboring gene gastrulation brain homeobox 1 Neighboring gene ankyrin repeat and SOCS box containing 10

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041756.1 Reference Mmul_10 Primary Assembly

    Range
    177089081..177145799
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028846482.1 → XP_028702315.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X7

    Conserved Domains (4) summary
    cd01250
    Location:55 → 299
    PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
    sd00045
    Location:443 → 473
    ANK; ANK repeat [structural motif]
    cd08855
    Location:315 → 424
    ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
    pfam12796
    Location:443 → 533
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_015135298.2 → XP_014990784.2  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X9

    Conserved Domains (1) summary
    cd04103
    Location:129 → 286
    Centaurin_gamma; Centaurin gamma (CENTG) GTPase

  3. XM_015135299.2 → XP_014990785.2  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X10

    Conserved Domains (1) summary
    cd04103
    Location:129 → 286
    Centaurin_gamma; Centaurin gamma (CENTG) GTPase

  4. XM_028846480.1 → XP_028702313.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X5

    UniProtKB/TrEMBL
    G7MNH0
    Conserved Domains (5) summary
    cd04103
    Location:129 → 286
    Centaurin_gamma; Centaurin gamma (CENTG) GTPase
    cd01250
    Location:402 → 543
    PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
    sd00045
    Location:687 → 717
    ANK; ANK repeat [structural motif]
    cd08855
    Location:559 → 668
    ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
    pfam12796
    Location:687 → 777
    Ank_2; Ankyrin repeats (3 copies)

  5. XM_015135295.2 → XP_014990781.2  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X2

    UniProtKB/TrEMBL
    G7MNH0
    Conserved Domains (5) summary
    cd04103
    Location:129 → 286
    Centaurin_gamma; Centaurin gamma (CENTG) GTPase
    cd01250
    Location:402 → 646
    PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
    sd00045
    Location:790 → 820
    ANK; ANK repeat [structural motif]
    cd08855
    Location:662 → 771
    ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
    pfam12796
    Location:790 → 880
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_028846481.1 → XP_028702314.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X6

    Conserved Domains (1) summary
    cd04103
    Location:308 → 465
    Centaurin_gamma; Centaurin gamma (CENTG) GTPase

  7. XM_028846477.1 → XP_028702310.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    G7MNH0
    Conserved Domains (5) summary
    cd01250
    Location:173 → 417
    PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
    sd00045
    Location:561 → 591
    ANK; ANK repeat [structural motif]
    cd08855
    Location:433 → 542
    ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
    pfam12796
    Location:561 → 651
    Ank_2; Ankyrin repeats (3 copies)
    cl38936
    Location:1 → 57
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  8. XM_028846478.1 → XP_028702311.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X3

    Conserved Domains (5) summary
    cd01250
    Location:173 → 360
    PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
    sd00045
    Location:504 → 534
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:504 → 594
    Ank_2; Ankyrin repeats (3 copies)
    cd08855
    Location:376 → 485
    ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
    cl21455
    Location:1 → 57
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  9. XM_028846479.1 → XP_028702312.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X4

    Conserved Domains (5) summary
    cd01250
    Location:173 → 314
    PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
    sd00045
    Location:458 → 488
    ANK; ANK repeat [structural motif]
    pfam12796
    Location:458 → 548
    Ank_2; Ankyrin repeats (3 copies)
    cd08855
    Location:330 → 439
    ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
    cl21455
    Location:1 → 57
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  10. XM_028846483.1 → XP_028702316.1  arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 isoform X8

    Conserved Domains (4) summary
    cd01250
    Location:55 → 196
    PH_AGAP; Arf-GAP with GTPase, ANK repeat and PH domain-containing protein Pleckstrin homology (PH) domain
    sd00045
    Location:340 → 370
    ANK; ANK repeat [structural motif]
    cd08855
    Location:212 → 321
    ArfGap_AGAP3; ArfGAP with GTPase domain, ANK repeat and PH domain 3
    pfam12796
    Location:340 → 430
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
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